Extracellular matrix remodeling and cardiac fibrosis

L Li, Q Zhao, W Kong - Matrix biology, 2018 - Elsevier
Cardiac fibrosis, characterized by excessive deposition of extracellular matrix (ECM)
proteins in the myocardium, distorts the architecture of the myocardium, facilitates the …

Metallic nanoparticles as X-Ray computed tomography (CT) contrast agents: A review

N Aslan, B Ceylan, MM Koç, F Findik - Journal of Molecular Structure, 2020 - Elsevier
X-ray computed tomography vastly used in both medical purposes and in the research of
biological and non-biological materials/samples. Some of the medical applications …

[HTML][HTML] Molecular imaging of cardiac remodelling after myocardial infarction

D Curley, B Lavin Plaza, AM Shah… - Basic research in …, 2018 - Springer
Myocardial infarction and subsequent heart failure is a major health burden associated with
significant mortality and morbidity in western societies. The ability of cardiac tissue to …

Evaluation of X‐ray tomography contrast agents: A review of production, protocols, and biological applications

MM Koç, N Aslan, AP Kao… - Microscopy research and …, 2019 - Wiley Online Library
X‐ray computed tomography is a strong tool that finds many applications both in medical
applications and in the investigation of biological and nonbiological samples. In the clinics …

Unparalleled contribution of technetium-99m to medicine over 5 decades

WC Eckelman - JACC: Cardiovascular Imaging, 2009 - jacc.org
Since the first tracer study by George C. de Hevesy in 1923, in which he used the tracer
principle to study the absorption and translocation of lead nitrate with Pb-212 (1) …

Syntheses and characterization of lisinopril-coated gold nanoparticles as highly stable targeted CT contrast agents in cardiovascular diseases

WE Ghann, O Aras, T Fleiter, MC Daniel - Langmuir, 2012 - ACS Publications
Lisinopril was used as the targeting moiety to prepare gold nanoparticle-based functional
CT contrast agents. Pure lisinopril, thioctic acid–lisinopril conjugate, and reduced thioctic …

The changing face of nuclear cardiology: guiding cardiovascular care toward molecular medicine

RA Werner, JT Thackeray, J Diekmann… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Radionuclide imaging of myocardial perfusion, function, and viability has been established
for decades and remains a robust, evidence-based and broadly available means for clinical …

Molecular imaging of the cardiac extracellular matrix

HJ de Haas, E Arbustini, V Fuster, CM Kramer… - Circulation …, 2014 - Am Heart Assoc
In almost all cardiac diseases, an increase in extracellular matrix (ECM) deposition or
fibrosis occurs, mostly consisting of collagen I. Whereas replacement fibrosis follows …

The glycine deportation system and its pharmacological consequences

D Beyoğlu, JR Idle - Pharmacology & therapeutics, 2012 - Elsevier
The glycine deportation system is an essential component of glycine catabolism in man
whereby 400 to 800mg glycine per day are deported into urine as hippuric acid. The …

Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide

KP Maresca, JC Marquis, SM Hillier, G Lu… - Bioconjugate …, 2010 - ACS Publications
Single amino acid chelate (SAAC) systems for the incorporation of the M (CO) 3 moiety (M=
Tc/Re) have been successfully incorporated into novel synthetic strategies for …