Chemokines mediate numerous physiological and pathological processes related primarily
to cell homing and migration. The chemokine CXCL12, also known as stromal cell-derived …

Due to the prevalence of cardiovascular diseases, there is a large need for small diameter
vascular grafts that cannot be fulfilled using autologous vessels. Although medium to large …

Emerging clinical and experimental evidence demonstrates that neuroinflammation plays an
important role in cognitive impairment associated with neuropathic pain. However, how …

Chemokine ligand-receptor interactions play a pivotal role in cell attraction and cellular
trafficking, both in normal tissue homeostasis and in disease. In cancer, chemokine receptor …

The overexpression of the chemokine receptor CXCR4 plays an important role in oncology,
since together with its endogenous ligand, the stromal cell–derived factor (SDF1-α), CXCR4 …

Ischaemic preconditioning is one of the most potent experimental modalities known to
decrease infarct size after ischaemia and reperfusion. Much interest has been stimulated by …

Overexpressed neuropeptide receptors allow tumor visualization using eg radiolabeled
peptidic receptor ligands and positron emission tomography (PET) or single photon …

In developed countries, cancer is the second leading cause of death, being only surpassed
by cardiovascular diseases. To develop tumor-targeted tools to localize and treat cancer at …

The G-protein-coupled chemokine receptor CXCR4 generates signals that lead to cell
migration, cell proliferation, and other survival mechanisms that result in the metastatic …

Alleviating myocardial injury associated with ST elevation myocardial infarction is central to
improving the global burden of coronary heart disease. The chemokine stromal cell-derived …