[HTML][HTML] Is there a role for GPCR agonist radiotracers in PET neuroimaging?

M Colom, B Vidal, L Zimmer - Frontiers in Molecular Neuroscience, 2019 - frontiersin.org
Positron emission tomography (PET) is a molecular imaging modality that enables in vivo
exploration of metabolic processes and especially the pharmacology of neuroreceptors. G …

Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C] OMAR

DF Wong, H Kuwabara, AG Horti, V Raymont, J Brasic… - Neuroimage, 2010 - Elsevier
Several studies have examined the link between the cannabinoid CB1 receptor and several
neuropsychiatric illnesses, including schizophrenia. As such, there is a need for in vivo …

Whole-body biodistribution and radiation dosimetry of 18F-GE067: a radioligand for in vivo brain amyloid imaging

M Koole, DM Lewis, C Buckley… - Journal of Nuclear …, 2009 - Soc Nuclear Med
We have characterized the biodistribution and dosimetry of 18F-3′-F-6-OH-BTA1 (18F-
GE067), a newly developed radioligand to visualize and quantify amyloid burden, in healthy …

IMAGING STUDY: Prefrontal cortex morphometry in abstinent adolescent marijuana users: subtle gender effects

KL Medina, T McQueeny, BJ Nagel… - Addiction …, 2009 - Wiley Online Library
Adult human studies suggest frontal dysfunction associated with chronic marijuana (MJ) use,
but due to continued neuromaturation, adult studies may not generalize to adolescents. This …

Abnormal cerebellar morphometry in abstinent adolescent marijuana users

KL Medina, BJ Nagel, SF Tapert - Psychiatry Research: Neuroimaging, 2010 - Elsevier
BACKGROUND: Functional neuroimaging data from adults have, in general, found
frontocerebellar dysfunction associated with acute and chronic marijuana (MJ) use (Loeber …

Development of radioligands for in vivo imaging of type 1 cannabinoid receptors (CB1) in human brain

AG Horti, KV Laere - Current pharmaceutical design, 2008 - ingentaconnect.com
Cerebral cannabinoid receptor (CB1) and cannabinoid drugs constitute a vibrant field in
modern medicine and pharmacology. However, the physiological and pharmacological …

Whole-Body Biodistribution and Radiation Dosimetry of the Cannabinoid Type 2 Receptor Ligand [11C]-NE40 in Healthy Subjects

R Ahmad, M Koole, N Evens, K Serdons… - Molecular imaging and …, 2013 - Springer
Purpose The type 2 cannabinoid receptor (CB2R) is part of the human endocannabinoid
system and is involved in central and peripheral inflammatory processes. In vivo imaging of …

[HTML][HTML] Comparison of cannabinoid CB1 receptor binding in adolescent and adult rats: a positron emission tomography study using [18F] MK-9470

M Verdurand, V Nguyen, D Stark, D Zahra… - International journal of …, 2011 - hindawi.com
Despite the important role of cannabinoid CB 1 receptors (CB 1 R) in brain development,
little is known about their status during adolescence, a critical period for both the …

Imaging brain metastasis patients with 18F-(2S, 4R)-4-fluoroglutamine

X Xu, H Zhu, F Liu, Y Zhang, J Yang… - Clinical Nuclear …, 2018 - journals.lww.com
Purpose There is a need for an alternative PET probe, which does not show normal brain
tissue uptake in the evaluation of metastasis to the brain. Therefore, we investigate the …

Sex differences in neuropsychological functioning are domain-specific in adolescent and young adult regular cannabis users

G Savulich, N Rychik, E Lamberth, M Hareli… - Journal of the …, 2021 - cambridge.org
Objective: Adolescence into young adulthood represents a sensitive period in which brain
development significantly diverges by sex. Regular cannabis use by young people is …