Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges

Y Hoshida, BC Fuchs… - Current cancer drug targets, 2012 - ingentaconnect.com
Chronic fibrotic liver diseases such as viral hepatitis eventually develop liver cirrhosis, which
causes occurrence of hepatocellular carcinoma (HCC). Given the limited therapeutic efficacy …

Intra-arterial therapies for hepatocellular carcinoma: where do we stand?

E Liapi, JFH Geschwind - Annals of surgical oncology, 2010 - Springer
Abstract Purpose and Design Intra-arterial therapies for unresectable hepatocellular
carcinoma (HCC) consist of a catheter-based group of treatments where therapeutic and/or …

Adjuvant 131I-metuximab for hepatocellular carcinoma after liver resection: a randomised, controlled, multicentre, open-label, phase 2 trial

J Li, J Xing, Y Yang, J Liu, W Wang, Y Xia… - The Lancet …, 2020 - thelancet.com
Background Effective adjuvant treatment after hepatectomy for hepatocellular carcinoma
(HCC) is an important area of research. Radioactive iodine (131 I)-labelled metuximab is a …

Adjuvant therapy with capecitabine postpones recurrence of hepatocellular carcinoma after curative resection: a randomized controlled trial

Y Xia, Y Qiu, J Li, L Shi, K Wang, T Xi, F Shen… - Annals of surgical …, 2010 - Springer
Background Postoperative recurrence of hepatocellular carcinoma (HCC) is a major
problem after surgical resection. To date, adjuvant chemotherapy or other adjuvant …

Yttrium-90 microsphere radioembolization for hepatocellular carcinoma

J Edeline, M Gilabert, E Garin, E Boucher, JL Raoul - Liver Cancer, 2015 - karger.com
Abstract Yttrium-90 (Y90) radioembolization is an emerging strategy to treat liver
malignancies, and clinical data supporting its use have accumulated in recent years. Y90 …

Treatment of hepatocellular carcinoma with intra-arterial injection of radionuclides

JL Raoul, E Boucher, Y Rolland, E Garin - … Reviews Gastroenterology & …, 2010 - nature.com
Hepatocellular carcinoma (HCC) is becoming an important public health concern. Current
therapeutic options are limited and new treatments are therefore being developed. The intra …

Adjuvant chemolipiodolization reduces early recurrence derived from intrahepatic metastasis of hepatocellular carcinoma after hepatectomy

M Ueno, K Uchiyama, S Ozawa, S Hayami… - Annals of surgical …, 2011 - Springer
Background The recurrence of hepatocellular carcinoma is still high even after surgery. Two
general recurrence patterns occur: intrahepatic metastasis (IM) and multicentric …

Systematic Review and Meta-Analysis of Adjuvant I131 Lipiodol after Excision of Hepatocellular Carcinoma

R Furtado, M Crawford, C Sandroussi - Annals of Surgical Oncology, 2014 - Springer
Background Curative resection for hepatocellular carcinoma (HCC) has an 80% recurrence
at 5 years. Survival could be prolonged with adjuvant iodine 131 lipiodol. This systematic …

Intra-arterial injection of 131I-labeled Lipiodol for advanced hepatocellular carcinoma: a 7 years' experience

A Lintia-Gaultier, C Perret, C Ansquer… - Nuclear Medicine …, 2013 - journals.lww.com
Background Internal irradiation with iodine-131 (131 I)-labeled Lipiodol is one of the
currently available forms of palliative therapy for patients with advanced hepatocellular …

Adjuvant and chemopreventive therapies for resectable hepatocellular carcinoma: a literature review

JH Zhong, QL Zhong, LQ Li, H Li - Tumor Biology, 2014 - Springer
The recurrence rate of hepatocellular carcinoma (HCC) after potentially curative hepatic
resection (HR) is very high. Many clinical trials have explored the efficacy of several …