Smoking and pain: pathophysiology and clinical implications
Y Shi, TN Weingarten, CB Mantilla… - The Journal of the …, 2010 - pubs.asahq.org
Cigarette smoke, which serves as a nicotine delivery vehicle in humans, produces profound
changes in physiology. Experimental studies suggest that nicotine has analgesic properties …
changes in physiology. Experimental studies suggest that nicotine has analgesic properties …
Addiction‐related neuroadaptations following chronic nicotine exposure
The addiction‐relevant molecular, cellular, and behavioral actions of nicotine are derived
from its stimulatory effects on neuronal nicotinic acetylcholine receptors (nAChRs) in the …
from its stimulatory effects on neuronal nicotinic acetylcholine receptors (nAChRs) in the …
Smoking, nicotine and neuropsychiatric disorders
P Dome, J Lazary, MP Kalapos, Z Rihmer - Neuroscience & Biobehavioral …, 2010 - Elsevier
Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …
but unfortunately also the most prevalent. Although disproportionately high frequencies of …
[HTML][HTML] When your brain looks older than expected: combined lifestyle risk and BrainAGE
Lifestyle may be one source of unexplained variance in the great interindividual variability of
the brain in age-related structural differences. While physical and social activity may protect …
the brain in age-related structural differences. While physical and social activity may protect …
[HTML][HTML] Pathophysiology of nAChRs: limbic circuits and related disorders
Human epidemiological studies have identified links between nicotine intake and stress
disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for …
disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for …
Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity
P Trifilieff, D Martinez - Neuropharmacology, 2014 - Elsevier
Dependence to drugs of abuse is closely associated with impulsivity, or the propensity to
choose a lower, but immediate, reward over a delayed, but more valuable outcome. Here …
choose a lower, but immediate, reward over a delayed, but more valuable outcome. Here …
[HTML][HTML] Dual role of nicotine in addiction and cognition: a review of neuroimaging studies in humans
Substantial evidence demonstrates both nicotine's addiction liability and its cognition-
enhancing effects. However, the neurobiological mechanisms underlying nicotine's impact …
enhancing effects. However, the neurobiological mechanisms underlying nicotine's impact …
[HTML][HTML] Nicotine promotes tumor growth and metastasis in mouse models of lung cancer
R Davis, W Rizwani, S Banerjee, M Kovacs, E Haura… - PloS one, 2009 - journals.plos.org
Background Nicotine is the major addictive component of tobacco smoke. Although nicotine
is generally thought to have limited ability to initiate cancer, it can induce cell proliferation …
is generally thought to have limited ability to initiate cancer, it can induce cell proliferation …
Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects
Cigarette smoking is currently the leading cause of preventable deaths and disability
throughout the world, being responsible for about five million premature deaths/year …
throughout the world, being responsible for about five million premature deaths/year …
Brain imaging changes associated with risk factors for cardiovascular and cerebrovascular disease in asymptomatic patients
Reviews of imaging studies assessing the brain effects of vascular risk factors typically
include a substantial number of studies with subjects with a history of symptomatic …
include a substantial number of studies with subjects with a history of symptomatic …