[HTML][HTML] Molecular and functional imaging in cancer-targeted therapy: current applications and future directions

JW Bai, SQ Qiu, GJ Zhang - Signal Transduction and Targeted Therapy, 2023 - nature.com
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …

Importance of quantification for the analysis of PET data in oncology: review of current methods and trends for the future

G Tomasi, F Turkheimer, E Aboagye - Molecular Imaging and Biology, 2012 - Springer
In oncology, positron emission tomography (PET) is an important tool for tumour diagnosis
and staging, assessment of response to treatment and evaluation of the pharmacokinetic …

Whole-body parametric imaging of 18F-FDG PET using uEXPLORER with reduced scanning time

Y Wu, T Feng, Y Zhao, T Xu, F Fu… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Parametric imaging of the net influx rate (Ki) in 18F-FDG PET has been shown to provide
improved quantification and specificity for cancer detection compared with SUV imaging …

Decreased blood flow with increased metabolic activity: a novel sign of pancreatic tumor aggressiveness

G Komar, S Kauhanen, K Liukko, M Seppänen… - Clinical Cancer …, 2009 - AACR
Purpose: To study blood flow (BF) and metabolism in normal pancreas and in different
pancreatic lesions. We then determined the effect of these biomarkers on outcome in …

Patient-specific characterization of breast cancer hemodynamics using image-guided computational fluid dynamics

C Wu, DA Hormuth, TA Oliver, F Pineda… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
The overall goal of this study is to employ quantitative magnetic resonance imaging (MRI)
data to constrain a patient-specific, computational fluid dynamics (CFD) model of blood flow …

Hypoxia and its modification in bladder cancer: current and future perspectives

T Lodhi, YP Song, C West, P Hoskin, A Choudhury - Clinical Oncology, 2021 - Elsevier
Radiotherapy plays an essential role in the curative treatment of muscle-invasive bladder
cancer (MIBC). Hypoxia affects the response to MIBC radiotherapy, limiting radiocurability …

[HTML][HTML] [15O] H2O PET: Potential or Essential for Molecular Imaging?

RHJA Slart, TS Martinez-Lucio, HH Boersma… - Seminars in Nuclear …, 2023 - Elsevier
Imaging water pathways in the human body provides an excellent way of measuring
accurately the blood flow directed to different organs. This makes it a powerful diagnostic …

Feasibility of measuring human pancreatic perfusion in vivo using imaging techniques

Y Tsushima, M Miyazaki, A Taketomi-Takahashi… - Pancreas, 2011 - journals.lww.com
Objective: The objective of this study was to demonstrate the feasibility of pancreatic
perfusion computed tomography (CT) and review pancreatic perfusion measurements by …

[HTML][HTML] Non-invasive quantification of tumor blood flow in prostate cancer using 15O-H2O PET/CT

LP Tolbod, MM Nielsen, BG Pedersen… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Tumor blood flow (TBF) measurements in prostate cancer (PCa) provide an integrative index
of tumor growth, which could be important for primary diagnosis and therapy response …

[HTML][HTML] How to assess intra-and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardisation

O Gerke, MH Vilstrup, EA Segtnan, U Halekoh… - BMC Medical …, 2016 - Springer
Background Quantitative measurement procedures need to be accurate and precise to
justify their clinical use. Precision reflects deviation of groups of measurement from another …