Calcific aortic valve stenosis (CAVS) is common in the ageing population and set to become
an increasing economic and health burden. Once present, it inevitably progresses and has a …

There is renewed interest in 18F-NaF bone imaging with PET or PET/CT. The current brief
discussion focuses on the molecular mechanisms of 18F-NaF deposition in bone and …

Objectives: With combined positron emission tomography and computed tomography (CT),
we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F …

The Society of Nuclear Medicine (SNM) is an international scientific and professional
organization founded in 1954 to promote the science, technology, and practical application …

Background—The pathophysiology of aortic stenosis is incompletely understood, and the
relative contributions of valvular calcification and inflammation to disease progression are …

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by heterotopic
ossification (HO) in connective tissues and painful flare-ups. In the phase 2 LUMINA-1 trial …

Prostate-specific membrane antigen (PSMA) is a type II integral membrane protein
expressed on the surface of prostate cancer (PCa) cells, particularly in androgen …

The lack of efficient [18F] fluorination processes and target-specific organofluorine
chemotypes remains the major challenge of fluorine-18 positron emission tomography …

Background: Microcalcifications in atherosclerotic plaques are destabilizing, predict adverse
cardiovascular events, and are associated with increased morbidity and mortality. 18F …

The skeleton is one of the most common sites for metastatic disease, particularly from breast
and prostate cancer. Bone metastases are associated with considerable morbidity, and …