[HTML][HTML] Ocular indicators of Alzheimer's: exploring disease in the retina
Although historically perceived as a disorder confined to the brain, our understanding of
Alzheimer's disease (AD) has expanded to include extra-cerebral manifestation, with …
Alzheimer's disease (AD) has expanded to include extra-cerebral manifestation, with …
[HTML][HTML] Alzheimer's retinopathy: seeing disease in the eyes
The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …
Plasma phospholipids identify antecedent memory impairment in older adults
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
Ensembles of deep learning architectures for the early diagnosis of the Alzheimer's disease
Computer Aided Diagnosis (CAD) constitutes an important tool for the early diagnosis of
Alzheimer's Disease (AD), which, in turn, allows the application of treatments that can be …
Alzheimer's Disease (AD), which, in turn, allows the application of treatments that can be …
Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model
M Koronyo-Hamaoui, Y Koronyo, AV Ljubimov… - Neuroimage, 2011 - Elsevier
Noninvasive monitoring of β-amyloid (Aβ) plaques, the neuropathological hallmarks of
Alzheimer's disease (AD), is critical for AD diagnosis and prognosis. Current visualization of …
Alzheimer's disease (AD), is critical for AD diagnosis and prognosis. Current visualization of …
Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism
CC Rowe, U Ackerman, W Browne, R Mulligan… - The Lancet …, 2008 - thelancet.com
Background Amyloid-β (Aβ) plaque formation is a hallmark of Alzheimer's disease (AD) and
precedes the onset of dementia. Aβ imaging should allow earlier diagnosis, but clinical …
precedes the onset of dementia. Aβ imaging should allow earlier diagnosis, but clinical …
Predicting cognitive decline with deep learning of brain metabolism and amyloid imaging
For effective treatment of Alzheimer's disease (AD), it is important to identify subjects who
are most likely to exhibit rapid cognitive decline. We aimed to develop an automatic image …
are most likely to exhibit rapid cognitive decline. We aimed to develop an automatic image …
Aβ amyloid and glucose metabolism in three variants of primary progressive aphasia
GD Rabinovici, WJ Jagust, AJ Furst, JM Ogar… - Annals of …, 2008 - Wiley Online Library
Objective Alzheimer's disease (AD) is found at autopsy in up to one third of patients with
primary progressive aphasia (PPA), but clinical features that predict AD pathology in PPA …
primary progressive aphasia (PPA), but clinical features that predict AD pathology in PPA …
Amyloid imaging with 18F-florbetaben in Alzheimer disease and other dementias
VL Villemagne, K Ong, RS Mulligan… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Amyloid imaging with 18F-labeled radiotracers will allow widespread use, facilitating
research, diagnosis, and therapeutic development for Alzheimer disease. The purpose of …
research, diagnosis, and therapeutic development for Alzheimer disease. The purpose of …
Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD
GD Rabinovici, HJ Rosen, A Alkalay, J Kornak… - Neurology, 2011 - AAN Enterprises
Objective: To compare the diagnostic performance of PET with the amyloid ligand Pittsburgh
compound B (PiB-PET) to fluorodeoxyglucose (FDG-PET) in discriminating between …
compound B (PiB-PET) to fluorodeoxyglucose (FDG-PET) in discriminating between …