ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

PET/NIRF/MRI triple functional iron oxide nanoparticles

J Xie, K Chen, J Huang, S Lee, J Wang, J Gao, X Li… - Biomaterials, 2010 - Elsevier
Engineered nanoparticles with theranostic functions have attracted a lot of attention for their
potential role in the dawning era of personalized medicine. Iron oxide nanoparticles …

Multimodality molecular imaging of tumor angiogenesis

W Cai, X Chen - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging is a key component of 21st-century cancer management. The vascular
endothelial growth factor (VEGF)/VEGF receptor signaling pathway and integrin α v β 3, a …

Nanobodies in cancer

ER Verhaar, AW Woodham, HL Ploegh - Seminars in immunology, 2021 - Elsevier
For treatment and diagnosis of cancer, antibodies have proven their value and now serve as
a first line of therapy for certain cancers. A unique class of antibody fragments called …

Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature

W Cai, K Chen, ZB Li, SS Gambhir… - Journal of Nuclear …, 2007 - Soc Nuclear Med
To date, the in vivo imaging of quantum dots (QDs) has been mostly qualitative or
semiquantitative. The development of a dual-function PET/near-infrared fluorescence (NIRF) …

Immuno-PET: a navigator in monoclonal antibody development and applications

GAMS Van Dongen, GWM Visser… - The …, 2007 - academic.oup.com
Learning Objectives After completing this course, the reader will be able to: Discuss the
technical advances that have led to recent rapid developments in monoclonal antibody …

Antibody vectors for imaging

T Olafsen, AM Wu - Seminars in nuclear medicine, 2010 - Elsevier
Noninvasive molecular imaging approaches include nuclear, optical, magnetic resonance
imaging, computed tomography, ultrasound, and photoacoustic imaging, which require …

Chelator-Free 64Cu-Integrated Gold Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy

X Sun, X Huang, X Yan, Y Wang, J Guo, O Jacobson… - ACS …, 2014 - ACS Publications
Using positron emission tomography (PET) imaging to monitor and quantitatively analyze
the delivery and localization of Au nanomaterials (NMs), a widely used photothermal agent …

[HTML][HTML] Advances in immuno–positron emission tomography: antibodies for molecular imaging in oncology

SM Knowles, AM Wu - Journal of Clinical Oncology, 2012 - ncbi.nlm.nih.gov
Identification of cancer cell–surface biomarkers and advances in antibody engineering have
led to a sharp increase in the development of therapeutic antibodies. These same advances …