Imaging the vulnerable plaque

D Vancraeynest, A Pasquet, V Roelants… - Journal of the American …, 2011 - jacc.org
Cardiovascular diseases are still the primary causes of mortality in the United States and in
Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and …

Arithmetic of vulnerable plaques for noninvasive imaging

J Narula, P Garg, S Achenbach, S Motoyama… - Nature clinical practice …, 2008 - nature.com
Sudden cardiac death and acute myocardial infarction often occur as the first manifestation
of coronary artery disease. Otherwise asymptomatic individuals with subclinical …

2-deoxy-2-[18F]fluoro-d-mannose positron emission tomography imaging in atherosclerosis

N Tahara, J Mukherjee, HJ De Haas, AD Petrov… - Nature medicine, 2014 - nature.com
Progressive inflammation in atherosclerotic plaques is associated with increasing risk of
plaque rupture. Molecular imaging of activated macrophages with 2-deoxy-2-[18F] fluoro-d …

Molecular imaging of inflammation/infection: nuclear medicine and optical imaging agents and methods

A Signore, SJ Mather, G Piaggio, G Malviya… - Chemical …, 2010 - ACS Publications
Inflammatory diseases are a heterogeneous class of diseases that may be divided into acute
and chronic forms. They can affect multiple organs (systemic) or can be localized to one …

Imaging atherosclerosis and vulnerable plaque

MM Sadeghi, DK Glover, GM Lanza… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Identifying patients at high risk for an acute cardiovascular event such as myocardial
infarction or stroke and assessing the total atherosclerotic burden are clinically important …

Imaging inflammation: molecular strategies to visualize key components of the inflammatory cascade, from initiation to resolution

DA Dorward, CD Lucas, AG Rossi, C Haslett… - Pharmacology & …, 2012 - Elsevier
Dysregulation of inflammation is central to the pathogenesis of innumerable human
diseases. Understanding and tracking the critical events in inflammation are crucial for …

Atherosclerosis plaque heterogeneity and response to therapy detected by in vivo molecular imaging of matrix metalloproteinase activation

M Razavian, S Tavakoli, J Zhang, L Nie… - Journal of nuclear …, 2011 - Soc Nuclear Med
Matrix metalloproteinases (MMPs) play a key role in the development of atherosclerosis and
its complications. In vivo detection and quantification of MMP activation can help track the …

Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo

T Quillard, K Croce, FA Jaffer… - Thrombosis and …, 2011 - thieme-connect.com
Macrophages contribute pivotally to cardiovascular diseases (CVD), notably to
atherosclerosis. Imaging of macrophages in vivo could furnish new tools to advance …

An in vitro evaluation of inflammation response of titanium functionalized with heparin/fibronectin complex

G Li, P Yang, X Guo, N Huang, R Shen - Cytokine, 2011 - Elsevier
Immobilization of biomolecules with a variety of biological functions has been a promising
method to improve the biocompatibility of biomaterials. However, little is known about their …

A sensitive sandwich-type immunosensor for the detection of MCP-1 based on a rGO-TEPA-Thi-Au nanocomposite and novel RuPdPt trimetallic nanoalloy particles

W Mao, J He, Z Tang, C Zhang, J Chen, J Li… - Biosensors and …, 2019 - Elsevier
A novel electrochemical immunosensor was proposed for the detection of monocyte
chemoattractant protein-1 (MCP-1), a biomarker of cardiovascular disease. Due to thionine …