Use of nicorandil in cardiovascular disease and its optimization

S Horinaka - Drugs, 2011 - Springer
Nicorandil, a unique dual pharmacological mechanism anti-anginal agent with adenosine
triphosphate sensitive potassium (K ATP) channel agonist and nitrate-like properties …

[HTML][HTML] Nicorandil: a drug with ongoing benefits and different mechanisms in various diseased conditions

LA Ahmed - Indian Journal of Pharmacology, 2019 - journals.lww.com
Nicorandil is a well-known antianginal agent, which has been recommended as one of the
second-line treatments for chronic stable angina as justified by the European guidelines. It …

[HTML][HTML] Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction

Y Sakata, D Nakatani, M Shimizu, S Suna, M Usami… - Journal of …, 2012 - Elsevier
BACKGROUND: Previous studies showed that nicorandil can reduce coronary events in
patients with coronary artery disease. However, it is unclear whether oral nicorandil …

Effect of nicorandil treatment adjunctive to percutaneous coronary intervention in patients with acute myocardial infarction: a systematic review and meta-analysis

J Zhou, J Xu, A Cheng, P Li… - Journal of International …, 2020 - journals.sagepub.com
Objective There is controversy whether nicorandil treatment has cardioprotective effects in
patients with acute myocardial infarction (AMI) following percutaneous coronary intervention …

Nicorandil Treatment in Patients With Acute Myocardial Infarction A Meta-Analysis

K Iwakura, H Ito, A Okamura, Y Koyama, M Date… - Circulation …, 2009 - jstage.jst.go.jp
Background: It is controversial as to whether nicorandil would have cardioprotective effects
in patients with acute myocardial infarction (AMI) who are undergoing reperfusion therapy. A …

Pharmacological intervention for prevention of left ventricular remodeling and improving prognosis in myocardial infarction

H Ishii, T Amano, T Matsubara, T Murohara - Circulation, 2008 - Am Heart Assoc
Early reperfusion of totally occluded coronary arteries with thrombolysis and/or
percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) reduces …

Nicorandil attenuates ventricular dysfunction and organ injury after cardiopulmonary bypass

YW Peng, T Major, KB Deatrick, A Mohammed… - International Journal of …, 2022 - Elsevier
Background Nicorandil, an adenosine triphosphate-sensitive potassium channel agonist
and nitric oxide donor, is a coronary vasodilator used to treat ischemia-induced chest pain …

[HTML][HTML] Meta-analysis of Nicorandil effectiveness on myocardial protection after percutaneous coronary intervention

XT Zhao, CF Zhang, QJ Liu - BMC cardiovascular disorders, 2019 - Springer
Background Using the current meta-analysis as well as systematic review, to determine the
curative effect of Nicorandil in comparison of no Nicorandil after elective percutaneous …

[HTML][HTML] Altered sympathetic nervous system signaling in the diabetic heart: emerging targets for molecular imaging

JT Thackeray, RS Beanlands… - American Journal of …, 2012 - ncbi.nlm.nih.gov
Diabetes is commonly associated with increased risk of cardiovascular morbidity and
mortality. Perturbations in sympathetic nervous system (SNS) signaling have been linked to …

[PDF][PDF] Sustained nicorandil administration reduces the infarct size in ST-segment elevation myocardial infarction patients with primary percutaneous coronary …

S Wang, Y Duan, X Feng, L Liu, Z Shi… - Anatolian Journal of …, 2019 - jag.journalagent.com
Objective: Currently, there is still no effective strategy to diminish the infarct size (IS) in
patients with ST-segment elevation myocardial infarction (STEMI). According to a previous …