International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and …

RT Jensen, JF Battey, ER Spindel, RV Benya - Pharmacological reviews, 2008 - ASPET
The mammalian bombesin receptor family comprises three G protein-coupled heptahelical
receptors: the neuromedin B (NMB) receptor (BB1), the gastrin-releasing peptide (GRP) …

Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states

N Gonzalez, TW Moody, H Igarashi, T Ito… - Current Opinion in …, 2008 - journals.lww.com
Bombesin-related peptides and their receptors: recent advanc... : Current Opinion in
Endocrinology, Diabetes and Obesity Bombesin-related peptides and their receptors: recent …

[HTML][HTML] Radiolabeled peptides: valuable tools for the detection and treatment of cancer

M Fani, HR Maecke, SM Okarvi - Theranostics, 2012 - ncbi.nlm.nih.gov
Human cancer cells overexpress many peptide receptors as molecular targets.
Radiolabeled peptides that bind with high affinity and specificity to the receptors on tumor …

Pilot comparison of 68Ga-RM2 PET and 68Ga-PSMA-11 PET in patients with biochemically recurrent prostate cancer

R Minamimoto, S Hancock, B Schneider… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Glu-NH-CO-NH-Lys-(Ahx)-[68Ga (HBED-CC)](68Ga-PSMA-11) is a PET tracer that can
detect prostate cancer relapses and metastases by binding to the extracellular domain of …

Expression of the gastrin‐releasing peptide receptor, the prostate stem cell antigen and the prostate‐specific membrane antigen in lymph node and bone metastases …

HJK Ananias, MC van den Heuvel, W Helfrich… - The …, 2009 - Wiley Online Library
OBJECTIVE Cell membrane antigens like the gastrin‐releasing peptide receptor (GRPR),
the prostate stem cell antigen (PSCA), and the prostate‐specific membrane antigen (PSMA) …

Prostate cancer relevant antigens and enzymes for targeted drug delivery

A Barve, W Jin, K Cheng - Journal of controlled release, 2014 - Elsevier
Chemotherapy is one of the most widely used approaches in combating advanced prostate
cancer, but its therapeutic efficacy is usually insufficient due to poor specificity and …

Bombesin receptor-mediated imaging and cytotoxicity: review and current status

V Sancho, A Di Florio, TW Moody… - Current drug …, 2011 - ingentaconnect.com
The three mammalian bombesin (Bn) receptors (gastrin-releasing peptide [GRP] receptor,
neuromedin B [NMB] receptor, BRS-3) are one of the classes of G protein-coupled receptors …

Targeting GRPR in urological cancers—from basic research to clinical application

R Mansi, A Fleischmann, HR Mäcke… - Nature reviews Urology, 2013 - nature.com
Gastrin releasing peptide (GRP) is a regulatory peptide that acts through its receptor (GRPR)
to regulate physiological functions in various organs. GRPR is overexpressed in neoplastic …

68Ga-labeled NOTA-RGD-BBN peptide for dual integrin and GRPR-targeted tumor imaging

Z Liu, G Niu, F Wang, X Chen - European journal of nuclear medicine and …, 2009 - Springer
Abstract Purpose Radiolabeled Arg-Gly-Asp (RGD) and bombesin (BBN) peptide analogs
have been extensively investigated for the imaging of tumor integrin α v β 3 and gastrin …

Multifunctional targeted therapy system based on 99mTc/177Lu‐labeled gold nanoparticles‐Tat(49–57)‐Lys3‐bombesin internalized in nuclei of prostate cancer …

N Jiménez‐Mancilla, G Ferro‐Flores… - Journal of Labelled …, 2013 - Wiley Online Library
Radiolabeled gold nanoparticles may function simultaneously as radiotherapy and thermal
ablation systems. The gastrin‐releasing peptide receptor (GRP‐r) is overexpressed in …