Tumour responses to treatment are still largely assessed from imaging measurements of
reductions in tumour size. However, this can take several weeks to become manifest and in …

Molecular imaging of tumor metabolism has gained considerable interest, since preclinical
studies have indicated a close relationship between the activation of various oncogenes and …

Purpose The aim of this study was to determine the impact of the main clinicopathological
and biological prognostic factors of breast cancer on 18 F-fluorodeoxyglucose (FDG) uptake …

It is hoped that in the not too distant future, noninvasive imaging–based molecular
interrogation and characterization of tumors can improve our fundamental understanding of …

Objective Using integrated 18F-fluorodeoxyglucose positron emission
tomography/computed tomography fusion imaging (18F-FDG PET/CT), the clinical …

Unique sensitivity of tumor cells to the inhibition of glycolysis is a good target for anticancer
therapy. Here, we demonstrate that the pharmacologically activated tumor suppressor p53 …

The cancer cell phenotype has been summarized in six hallmarks [D. Hanahan, RA
Weinberg, The hallmarks of cancer, Cell 100 (1)(2000) 57–70]. Following the conceptual …

Postoperative prognosis is better for hormonal receptor-positive breast cancer than for other
phenotypes; however, there are no definitive predictive factors for relapse or survival. This …

Recently, the inevitable metabolic reprogramming experienced by cancer cells as a result of
the onset of cellular proliferation has been added to the list of hallmarks of the cancer cell …

Enhanced glycolysis is observed in most of cancerous cells and tissues, called as the
Warburg effect. Recent advance in senescent biology implicates that the metabolic shift to …