Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

The eradication of cancer remains a vexing problem despite recent advances in our
understanding of the molecular basis of neoplasia. One therapeutic approach that has …

Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy
of disease has been the driving force behind burgeoning research interests in the design of …

Bioconjugates used in internal radiotherapy exhibit heterogeneous distributions in organs
and tumors, implying a risk of nonuniform dose distribution in therapeutic applications using …

203Pb and 212Pb have emerged as promising theranostic isotopes for image-guided α-
particle radionuclide therapy for cancers. Here, we report a cyclen-based Pb specific …

Receptor-targeted image-guided Radionuclide Therapy (TRT) is increasingly recognized as
a promising approach to cancer treatment. In particular, the potential for clinical translation of …

Minimal residual disease (MRD) has become an increasingly prevalent and important entity
in multiple myeloma (MM). Despite deepening responses to frontline therapy, roughly 75 …

Radiation therapy is an effective cancer treatment option in conjunction with chemotherapy
and surgery. Emerging individualized internal and systemic radiation treatment promises …

A method for preparation of Pb-212 and Pb-203 labeled chelator-modified peptide-based
radiopharmaceuticals for cancer imaging and radionuclide therapy has been developed and …

A new method utilizing alpha particles to treat solid tumors is presented. Tumors are treated
with interstitial radioactive sources which continually release short-lived alpha emitting …