Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Affibody molecules are a class of engineered affinity proteins with proven potential for
therapeutic, diagnostic and biotechnological applications. Affibody molecules are small (6.5 …

Purpose The aim of the present paper is to review the role of HER2 antibodies, affibodies
and nanobodies as vehicles for imaging and therapy approaches in breast cancer, including …

Antibodies have been the paradigm of binding proteins with desired specificities for more
than one century and during the past decade their recombinant or humanized versions have …

Affibody molecules can be used as tools for molecular recognition in diagnostic and
therapeutic applications. There are several preclinical studies reported on diagnostic and …

In recent years, classical antibody‐based affinity reagents have been challenged by novel
types of binding proteins developed by combinatorial protein engineering principles. One of …

Nanoparticles exhibiting the localized surface plasmon resonance (LSPR) phenomenon are
promising tools for diagnostics and cancer treatment. Among widely used metal …

Slow-clearing, tumor-targeting proteins such as monoclonal antibodies typically exhibit high
tumor accumulation but low tissue contrast, whereas intermediate-sized proteins such as …

A radiolabeled anti-HER2 Affibody molecule (ZHER2: 342) targets HER2-expressing
xenografts with high selectivity and gives good imaging contrast. However, the small size (∼ …

Abstract The Affibody molecule ZHER2: 342-pep2, site-specifically and homogeneously
conjugated with a 1, 4, 7, 10-tetra-azacylododecane-N, N′, N ″, N‴-tetraacetic acid …