Extracellular adenosine is a potent immunosuppressor that accumulates during tumor
growth. We performed proof-of-concept studies investigating the therapeutic potential and …

The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …

Glioblastoma (GBM) treatment includes, when possible, surgical resection of the tumor
followed by radiotherapy and oral chemotherapy with temozolomide, however recurrences …

Human mesenchymal stem cells (hMSC) are a heterogeneous cell population, which is
reflected in varying morphological and biological properties. Three subpopulations with …

Ecto-5'-nucleotidase (eN, CD73) mediates extracellular adenosine production from 5'-AMP.
Non-enzymatic functions of eN have also been reported. The aim of the study was to …

Increasing evidence points out that genetic alteration does not guarantee the development
of a tumor and indicates that complex interactions of tumor cells with the microenvironment …

Glioblastoma multiforme is one of the most malignant types of cancer. This is mainly due to a
cell subpopulation with an extremely aggressive potential, called glioblastoma stem-like …

Objective Galvanotaxis, the migratory response of cells in response to electrical stimulation,
has been implicated in development and wound healing. The use of mesenchymal stem …

Renal cell carcinoma (RCC) is a common tissue tumor that occurs across all age groups and
has become one of the types of cancer with the fastest increasing incidence. Due to the …

Abstract Equilibrative nucleoside transporter 3 (ENT3) belongs to the solute carrier family
29. Nucleoside transporters encoded by ENT3 play an important role in the uptake of …