Glycosylation changes that occur in cancer often lead to the expression of tumour-
associated carbohydrate antigens. In breast cancer, these antigens are usually associated …

Prostate cancer is a common cancer in men and continues to be a major health problem.
Imaging plays an important role in the clinical management of patients with prostate cancer …

Locally advanced pancreatic tumours are highly resistant to conventional
radiochemotherapy. Here we show that such resistance can be surmounted by an injectable …

Despite recent advances, advanced prostate cancer is suboptimally responsive to current
chemotherapeutic agents. Radiolabeled monoclonal antibody therapy that targets prostate …

Prostate cancer is the most common non-cutaneous malignancy affecting men in the US,
leading to significant morbidity and mortality. While significant therapeutic advances have …

Ovarian cancer is one of the most frequent solid tumor that shows clearly biphasic behaviour
in response to chemotherapy, with the majority of patients who achieved complete remission …

Combination radioimmunotherapy is an emerging approach for the treatment of solid tumors
where radio immunotherapy alone has proven to be reasonably ineffective …

Germline antibodies, the initial set of antibodies produced by the immune system, are critical
for host defense, and information about their binding properties can be useful for designing …

Development of targeted radionuclide therapy with 90Y labeled antibodies and peptides has
gained momentum in the past decade due to the successes of 90Y-ibritumomab tiuxetan …

This article reviews the development of radioimmunoconjugates as a new class of cancer
therapeutics. Numerous conjugates involving different antigen targets, antibody forms …