[HTML][HTML] Review of the correlation of LAT1 with diseases: mechanism and treatment
J Zhang, Y Xu, D Li, L Fu, X Zhang, Y Bao… - Frontiers in …, 2020 - frontiersin.org
LAT1 is a member of the system L transporter family. The main role of the LAT1 is to
transport specific amino acids through cell membranes to provide nutrients to cells and …
transport specific amino acids through cell membranes to provide nutrients to cells and …
[HTML][HTML] Nutritional and medicinal aspects of d-amino acids
M Friedman, CE Levin - Amino acids, 2012 - Springer
This paper reviews and interprets a method for determining the nutritional value of d-amino
acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic …
acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic …
Differences in Transport Mechanisms of trans-1-Amino-3-[18F]Fluorocyclobutanecarboxylic Acid in Inflammation, Prostate Cancer, and Glioma Cells: Comparison with l-[Methyl-11C] …
S Oka, H Okudaira, M Ono, DM Schuster… - Molecular imaging and …, 2014 - Springer
Purpose We aimed to elucidate trans-1-amino-3-[18 F] fluorocyclobutanecarboxylic acid (ant
i-[18 F] FACBC) uptake mechanisms in inflammatory and tumor cells, in comparison with …
i-[18 F] FACBC) uptake mechanisms in inflammatory and tumor cells, in comparison with …
Non-natural amino acids for tumor imaging using positron emission tomography and single photon emission computed tomography
J McConathy, MM Goodman - Cancer and Metastasis Reviews, 2008 - Springer
Amino acids are required nutrients for proliferating tumor cells, and amino acid transport is
upregulated in many tumor types. Studies of radiolabeled amino acids in animals and …
upregulated in many tumor types. Studies of radiolabeled amino acids in animals and …
High-throughput screening with nanoimprinting 3D culture for efficient drug development by mimicking the tumor environment
Y Yoshii, T Furukawa, A Waki, H Okuyama, M Inoue… - Biomaterials, 2015 - Elsevier
Anti-cancer drug development typically utilizes high-throughput screening with two-
dimensional (2D) cell culture. However, 2D culture induces cellular characteristics different …
dimensional (2D) cell culture. However, 2D culture induces cellular characteristics different …
[HTML][HTML] 18F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation
S Nozaki, Y Nakatani, A Mawatari, N Shibata… - Scientific reports, 2019 - nature.com
Positron emission tomography (PET) imaging can assist in the early-phase diagnostic and
therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET …
therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET …
Improved Radiosynthesis and Biological Evaluations of L- and D-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of IDO-Mediated Kynurenine Pathway of Tryptophan …
Purpose Tryptophan metabolism via indoleamine 2, 3-dioxygenase (IDO)-mediated
kynurenine pathway plays a role in immunomodulation and has been emerging as a …
kynurenine pathway plays a role in immunomodulation and has been emerging as a …
Proliferation markers for the differential diagnosis of tumor and inflammation
A Waarde, PH Elsinga - Current pharmaceutical design, 2008 - ingentaconnect.com
FDG, the most common radiopharmaceutical for PET imaging in oncology, is not tumor-
specific. Significant tracer accumulation can also occur in viral, bacterial and fungal …
specific. Significant tracer accumulation can also occur in viral, bacterial and fungal …
Uptake of two 10B‐compounds in liver metastases of colorectal adenocarcinoma for extracorporeal irradiation with boron neutron capture therapy (EORTC Trial …
Disseminated metastases of colorectal cancer in liver are incurable. The trial EORTC 11001
investigates whether autotransplantation after extracorporeal irradiation of the liver by boron …
investigates whether autotransplantation after extracorporeal irradiation of the liver by boron …
[BOOK][B] Electronics for radiation detection
K Iniewski - 2018 - taylorfrancis.com
There is a growing need to understand and combat potential radiation damage problems in
semiconductor devices and circuits. Assessing the billion-dollar market for detection …
semiconductor devices and circuits. Assessing the billion-dollar market for detection …