Pigmented ocular tissues contain melanin within the intracellular melanosomes. Drugs bind
to melanin at varying extent that ranges from no binding to extensive binding. Binding may …

Simple Summary Uveal melanoma is the most prevalent intraocular tumor in adults, derived
from melanocytes; the liver is the most common site of its metastases. Due to troublesome …

Melanoma is an aggressive skin cancer with worldwide increasing incidence. Development
of positron emission tomography (PET) probes for early detection of melanoma is critical for …

The aim of this study was to evaluate the novel probe 18F-6-fluoro-N-[2-(diethylamino) ethyl]
pyridine-3-carboxamide (18F-MEL050) for the imaging of primary and metastatic melanoma …

N-(2-(diethylamino)-ethyl)-18F-5-fluoropicolinamide (18F-P3BZA) is a radiotracer that
demonstrates high binding selectivity and affinity in melanoma. The aim of the present study …

Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset
of such tumors is insidious, such that affected patients often have no pain or obvious …

INTRODUCTION: Diagnosis of malignant melanoma is critical, since a patient's prognosis is
poor. Previous studies have shown that 64Cu-and 86Y-DOTA-ReCCMSH (Arg11) have the …

Different types of imaging modalities are used in the diagnosis of ocular cancer. Selection of
an imaging modality is based on the features of a tumor as well as the inherent …

The aim of molecular imaging techniques is the visualization of molecular processes and
functional changes in living animals and human patients before morphological changes …

Objectives We investigated the relationship between overall survival of patients and
pretreatment [18 F]-2-fluorodeoxyglucose (18 F-FDG) uptake, assessed by positron …