Tumor cell metabolism imaging

C Plathow, WA Weber - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging of tumor metabolism has gained considerable interest, since preclinical
studies have indicated a close relationship between the activation of various oncogenes and …

O-(2-[18F] fluoroethyl)-L-tyrosine: uptake mechanisms and clinical applications

KJ Langen, K Hamacher, M Weckesser, F Floeth… - Nuclear medicine and …, 2006 - Elsevier
O-(2-[18F] fluoroethyl)-l-tyrosine (FET) is a promising tracer for PET that has demonstrated
convincing results especially in the diagnostics of brain tumors. In contrast to other …

[HTML][HTML] Clinical applications of FDG PET and PET/CT in head and neck cancer

A Al-Ibraheem, A Buck, BJ Krause, K Scheidhauer… - Journal of …, 2009 - hindawi.com
18F-FDG PET plays an increasing role in diagnosis and management planning of head and
neck cancer. Hybrid PET/CT has promoted the field of molecular imaging in head and neck …

Comparison of visual and semiquantitative analysis of 18F-FDOPA-PET/CT for recurrence detection in glioblastoma patients

K Herrmann, J Czernin, T Cloughesy, A Lai… - Neuro …, 2014 - academic.oup.com
Background Amino acid transport imaging with 18F-FDOPA PET is increasingly used for
detection of glioblastoma recurrence. However, a standardized image interpretation for 18F …

Functional imaging for radiation treatment planning, response assessment, and adaptive therapy in head and neck cancer

P Bhatnagar, M Subesinghe, C Patel, R Prestwich… - Radiographics, 2013 - pubs.rsna.org
Patients with squamous cell carcinomas (SCCs) of the head and neck are increasingly
treated nonsurgically. Imaging plays a critical role in helping define the targets for radiation …

PET-CT for response assessment and treatment adaptation in head and neck cancer

J Bussink, CML van Herpen, JHAM Kaanders… - The lancet …, 2010 - thelancet.com
Preferred treatment strategies for advanced-stage squamous cell carcinoma of the head and
neck have shifted from surgery to organ-preservation approaches such as radiotherapy …

18F-FET PET differentiation of ring-enhancing brain lesions

FW Floeth, D Pauleit, M Sabel… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The aim of this study was to explore the differential diagnostic value of PET using the amino
acid O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) in patients with newly diagnosed solitary …

Nuclear imaging probes: from bench to bedside

HJ Wester - Clinical cancer research, 2007 - AACR
The availability of specific imaging probes is the nuclear fuel for molecular imaging by
positron emission tomography and single-photon emission computed tomography. These …

Radiohalogenated nonnatural amino acids as PET and SPECT tumor imaging agents

J McConathy, W Yu, N Jarkas, W Seo… - Medicinal research …, 2012 - Wiley Online Library
Radiohalogenated α‐amino acids are a diverse and useful class tumor imaging agents
suitable for positron emission tomography and single photon emission computed …

Non-natural amino acids for tumor imaging using positron emission tomography and single photon emission computed tomography

J McConathy, MM Goodman - Cancer and Metastasis Reviews, 2008 - Springer
Amino acids are required nutrients for proliferating tumor cells, and amino acid transport is
upregulated in many tumor types. Studies of radiolabeled amino acids in animals and …