Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Thiosemicarbazones as potent anticancer agents and their modes of action

B Shakya, PN Yadav - Mini Reviews in Medicinal Chemistry, 2020 - ingentaconnect.com
Thiosemicarbazones (TSCs) are a class of Schiff bases usually obtained by the
condensation of thiosemicarbazide with a suitable aldehyde or ketone. TSCs have been the …

Metal complexes of thiosemicarbazones for imaging and therapy

JR Dilworth, R Hueting - Inorganica Chimica Acta, 2012 - Elsevier
This review gives an account of the coordination chemistry of thiosemicarbazone ligands
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …

Anticancer activities of thiosemicarbazides/thiosemicarbazones: a review

S Arora, S Agarwal, S Singhal - 2014 - dr.ddn.upes.ac.in
There have been tremendous development in the chemotherapy of cancer and researches
are still developing new and more effective drugs to combat this disease …

Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition

BS Kumar, K Ravi, AK Verma, K Fatima… - Bioorganic & Medicinal …, 2017 - Elsevier
Naphthoquinones are naturally occurring biologically active entities. Practical de novo
syntheses of three naphthoquinones ie lawsone (1), lapachol (2), and β-lapachone (3b) …

A brief overview of metal complexes as nuclear imaging agents

DS MacPherson, K Fung, BE Cook… - Dalton …, 2019 - pubs.rsc.org
Metallic radionuclides have been instrumental in the field of nuclear imaging for over half a
century. While recent years have played witness to a dramatic rise in the use of radiometals …

Copper(II) Complexes with Highly Water-Soluble l- and d-Proline–Thiosemicarbazone Conjugates as Potential Inhibitors of Topoisomerase IIα

F Bacher, EA Enyedy, NV Nagy… - Inorganic …, 2013 - ACS Publications
Two proline–thiosemicarbazone bioconjugates with excellent aqueous solubility, namely, 3-
methyl-(S)-pyrrolidine-2-carboxylate-2-formylpyridine thiosemicarbazone [l-Pro-FTSC or (S) …

Thiosemicarbazone complexes as versatile medicinal chemistry agents: a review

EJ Siddiqui, I Azad, AR Khan, T Khan - Journal of drug delivery and …, 2019 - jddtonline.info
Objective: Thiosemicarbazones are Schiff based ligands of significant biological importance
and their biological relevance has been studied for a considerable amount of time period …

[HTML][HTML] Strong effect of copper (ii) coordination on antiproliferative activity of thiosemicarbazone–piperazine and thiosemicarbazone–morpholine hybrids

F Bacher, O Dömötör, A Chugunova, NV Nagy… - Dalton …, 2015 - pubs.rsc.org
In this study, 2-formylpyridine thiosemicarbazones and three different heterocyclic
pharmacophores were combined to prepare thiosemicarbazone–piperazine mPip-FTSC …

Fluorescent gallium and indium bis (thiosemicarbazonates) and their radiolabelled analogues: Synthesis, structures and cellular confocal fluorescence imaging …

RL Arrowsmith, PA Waghorn, MW Jones… - Dalton …, 2011 - pubs.rsc.org
New fluorescent and biocompatible aromatic Ga (III)-and In (III)-bis (thiosemicarbazonato)
complexes for dual mode optical and PET or SPECT molecular imaging have been …