The direct basal ganglia pathway is hyperfunctional in focal dystonia

K Simonyan, H Cho, A Hamzehei Sichani… - Brain, 2017 - academic.oup.com
Abstract See Fujita and Eidelberg (doi: 10.1093/brain/awx305) for a scientific commentary
on this article. Focal dystonias are the most common type of isolated dystonia. Although their …

Radiation dose estimates for carbon-11-labelled PET tracers

J van der Aart, WA Hallett, EA Rabiner… - Nuclear medicine and …, 2012 - Elsevier
INTRODUCTION: Carbon-11-labelled positron emission tomography (PET) tracers
commonly used in biomedical research expose subjects to ionising radiation. Dosimetry is …

[PDF][PDF] 11C dosimetry scans should be abandoned

P Zanotti-Fregonara, AA Lammertsma… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Before a new tracer can be used in clinical research, it is customary to perform dosimetry
scans in animals and humans to assess whether the radiation exposure is acceptable. The …

Biodistribution and radiation dosimetry of [11C]choline: a comparison between rat and human data

T Tolvanen, T Yli-Kerttula, T Ujula, A Autio… - European journal of …, 2010 - Springer
Abstract Purpose Methyl-11 C-choline ([11 C] choline) is a radiopharmaceutical used for
oncological PET studies. We investigated the biodistribution and biokinetics of [11 C] choline …

Suggested pathway to assess radiation safety of 11C-labeled PET tracers for first-in-human studies

P Zanotti-Fregonara, RB Innis - European journal of nuclear medicine and …, 2012 - Springer
Dear Sir, Before a new radioactive tracer can be used in humans, many national as well as
local Institutional Radiation Safety Committees often require that a biodistribution study be …

PET-based biodistribution and radiation dosimetry of epidermal growth factor receptor–selective tracer 11C-PD153035 in humans

N Liu, M Li, X Li, X Meng, G Yang, S Zhao… - Journal of Nuclear …, 2009 - Soc Nuclear Med
The present study estimated the biodistribution and radiation-absorbed dose of epidermal
growth factor receptor (EGFR) radioligand 11C-PD153035 in whole-body PET examinations …

Brain and whole-body imaging in rhesus monkeys of 11C-NOP-1A, a promising PET radioligand for nociceptin/orphanin FQ peptide receptors

Y Kimura, M Fujita, J Hong, TG Lohith… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Our laboratory developed (S)-3-(2′-fluoro-6′, 7′-dihydrospiro [piperidine-4, 4′-thieno
[3, 2-c] pyran]-1-yl)-2-(2-fluorobenzyl)-N-methylpropanamide (11C-NOP-1A), a new …

Human biodistribution and radiation dosimetry of 11C-(R)-PK11195, the prototypic PET ligand to image inflammation

J Hirvonen, A Roivainen, J Virta, S Helin… - European journal of …, 2010 - Springer
Purpose The positron emission tomography (PET) radiotracer 11 C-(R)-PK11195 allows the
in vivo imaging in humans of the translocator protein 18 kDa (TSPO), previously called …

[BOOK][B] Dopamine: endocrine and oncogenic functions

N Ben-Jonathan - 2020 - taylorfrancis.com
Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator
implicated in many neurological and psychiatric disorders. Outside the brain, dopamine …

Biodistribution and estimation of radiation-absorbed doses in humans for 13N-ammonia PET

C Yi, D Yu, X Shi, Q He, X Zhang, X Zhang - Annals of nuclear medicine, 2015 - Springer
Objective To evaluate the biodistribution of radiation-absorbed doses of 13 N-ammonia in
healthy people. Methods Five healthy human subjects underwent whole-body PET and CT …