Inflammatory diseases are a heterogeneous class of diseases that may be divided into acute
and chronic forms. They can affect multiple organs (systemic) or can be localized to one …

Timely and specific diagnosis of infectious diseases can be clinically challenging but
essential for the patient's outcome. Laboratory tests, such as a blood culture or urine …

Over the last forty years, a small group of commercial radiopharmaceuticals have found their
way into routine medical use, for the diagnostic imaging of patients with infection or …

Easy and early detection of infection and inflammation is essential for early and effective
treatment. In this study, PEGylated micelles were designed and both micelles and …

Purpose To evaluate the ability of polymeric nanocapsules (NCs) radiolabeled with
technetium-99m D, L-hexamethylpropyleneamine oxime (99m Tc–HMPAO) to identify …

INTRODUCTION: Interleukin (IL)-1 and IL-18 are potent proinflammatory cytokines in
inflammation-related diseases. Their actions are regulated by IL-1 receptor antagonist (IL …

Over the past 20 years, radiopharmaceutical research has brought to market a wide variety
of drugs that aid in the management of infection and inflammation. Finding the best clinical …

The current gold standard for imaging infection is radiolabeled white blood cells. For
reasons of safety, simplicity and cost, it would be desirable to have a receptor-specific ligand …

Abstract 2, 2′-[(8-hydroxyquinolin-7-yl) methylazanediyl] diacetic acid (HQMADA) was
synthesized via reaction of 8-hydroxyquinoline with iminodiacetic acid in presence of …

Purpose To investigate the biodistribution and the ability of stealth pH-sensitive liposomes
radiolabelled with 99m Tc to identify inflammatory regions in a rat focal inflammation model …