Cells are able to execute apoptosis by activating series of specific biochemical reactions.
One of the most prominent characteristics of cell death is the externalization of …

Despite recent progress, cardiovascular and allied metabolic disorders remain a worldwide
health challenge. We must identify new targets for therapy, develop new agents for clinical …

A quantum-dot-based nanoparticle is presented, allowing visualization of cell death and
activated platelets with fluorescence imaging and MRI. The particle exhibits intense …

Identifying patients at high risk for an acute cardiovascular event such as myocardial
infarction or stroke and assessing the total atherosclerotic burden are clinically important …

Acute rupture of vulnerable plaques frequently leads to myocardial infarction and stroke.
Within the last decades, several cellular and molecular players have been identified that …

Nuclear cardiology has experienced exponential growth within the past four decades with
converging capacity to diagnose and influence management of a variety of cardiovascular …

The rupture of atherosclerotic vulnerable plaques and subsequent formation of thrombi are
the main factors responsible for myocardial and cerebral infarctions. Because macrophage …

Phosphatidylethanolamine (PE) is a major component in the mammalian plasma
membrane. It is present mainly in the inner leaflet of the membrane bilayer in a viable …

Background—The accumulation of macrophages in inflamed atherosclerotic plaques has
long been recognized. In an attempt to develop an imaging agent for detection of vulnerable …

Lectinlike oxidized low-density lipoprotein (LDL) receptor 1 (LOX-1), a cell surface receptor
for oxidized LDL, has been implicated in vascular cell dysfunction related to plaque …