Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …

Multimodality molecular imaging continues to rapidly expand and is impacting many areas
of biomedical research as well as patient management. Reporter-gene assays have …

Heart failure is a leading cause of morbidity and mortality, and cardiac gene delivery has the
potential to provide novel therapeutic approaches. Adeno-associated virus serotype 9 …

Introduction In vivo tracking of the transplanted stem cells is important in pre-clinical
research of stem cell therapy for myocardial infarction. We examined the feasibility of …

Non-invasive in-vivo molecular genetic imaging developed over the past decade and
predominantly utilises radiotracer (PET, gamma camera, autoradiography), magnetic …

Although the success of sodium/iodide symporter (NIS) gene–based cancer therapy is
critically dependent on the level of radioiodide accumulation attained, recent evidence …

The Na+/I− symporter (NIS) has been proposed as an imaging reporter gene to ascertain the
expression of therapeutic genes in targeted tissues. In this study, we investigated whether …

Replication-incompetent adenovirus type 35 (rAd35) represents a potent vaccine carrier that
elicits strong, antigen-specific T-and B-cell responses in diverse preclinical models …

INTRODUCTION: Cell preparation procedures injurious to Na/I symporters (NIS) could deter
their usefulness for reporter gene assays and in vivo cell imaging. In this study, we …