Molecular imaging refers to the use of non-invasive imaging techniques to detect signals
that originate from molecules, often in the form of an injected tracer, and observe their …

Emission tomography provides three-dimensional, quantitative images of the distribution of
radiotracers used to mark physiological, metabolic, or pathological processes. Quantitative …

Background: The human anti-tumour necrosis factor (TNF) antibody infliximab binds to the
membrane TNF and subsequently induces apoptosis of activated lamina propria T …

Background Mouse models of inflammatory bowel diseases (IBD) are used to unravel the
pathophysiology of IBD and to study new treatment modalities, but their relationship to …

Purpose We compared the performance of three commercial small-animal μSPECT
scanners equipped with multipinhole general purpose (GP) and multipinhole high-resolution …

Dysregulation of inflammation is central to the pathogenesis of innumerable human
diseases. Understanding and tracking the critical events in inflammation are crucial for …

Small animal SPECT imaging systems have multiple potential applications in biomedical
research. Whereas SPECT data are commonly interpreted qualitatively in a clinical setting …

Several types of gene-and cell-based therapeutics are now emerging in the cancer
immunotherapy, transplantation, and regenerative medicine landscapes. Radionuclear …

Background Ulcerative colitis and Crohn's disease are the major chronic inflammatory bowel
diseases affecting the gastrointestinal tract in humans. Imaging techniques such as …

Inflammatory bowel disease (IBD) is associated with neutrophil infiltration into the mucosa
and crypt abscesses. The chemokine interleukin (IL)-8 [murine homologues (KC) and …