Current status of PET imaging in neuro-oncology

N Galldiks, P Lohmann, NL Albert… - Neuro-Oncology …, 2019 - academic.oup.com
Over the past decades, a variety of PET tracers have been used for the evaluation of patients
with brain tumors. For clinical routine, the most important clinical indications for PET imaging …

PET/CT imaging in cancer: current applications and future directions

MD Farwell, DA Pryma, DA Mankoff - Cancer, 2014 - Wiley Online Library
Positron emission tomography (PET) is a radiotracer imaging method that yields quantitative
images of regional in vivo biology and biochemistry. PET, now used in conjunction with …

Metabolic activity by 18F–FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC

K Kaira, T Higuchi, I Naruse, Y Arisaka, A Tokue… - European journal of …, 2018 - Springer
Background Nivolumab, an anti-programmed death-1 (PD-1) antibody, is administered in
patients with previously treated non-small cell lung cancer. However, little is known about …

Tumor cell metabolism imaging

C Plathow, WA Weber - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging of tumor metabolism has gained considerable interest, since preclinical
studies have indicated a close relationship between the activation of various oncogenes and …

O-(2-[18F] fluoroethyl)-L-tyrosine: uptake mechanisms and clinical applications

KJ Langen, K Hamacher, M Weckesser, F Floeth… - Nuclear medicine and …, 2006 - Elsevier
O-(2-[18F] fluoroethyl)-l-tyrosine (FET) is a promising tracer for PET that has demonstrated
convincing results especially in the diagnostics of brain tumors. In contrast to other …

[18F]-fluoro-ethyl-l-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma

M Hutterer, M Nowosielski, D Putzer, NL Jansen… - Neuro …, 2013 - academic.oup.com
Background To assess the sensitivity and specificity of [18F]-fluoro-ethyl-l-tyrosine (18F-FET)
PET in brain tumors and various non-neoplastic neurologic diseases. Methods We …

Improved detection of diffuse glioma infiltration with imaging combinations: a diagnostic accuracy study

N Verburg, T Koopman, MM Yaqub… - Neuro …, 2020 - academic.oup.com
Background Surgical resection and irradiation of diffuse glioma are guided by standard MRI:
T2/fluid attenuated inversion recovery (FLAIR)–weighted MRI for non-enhancing and T1 …

Imaging of amino acid transport in brain tumours: positron emission tomography with O-(2-[18F] fluoroethyl)-L-tyrosine (FET)

KJ Langen, G Stoffels, C Filss, A Heinzel, C Stegmayr… - Methods, 2017 - Elsevier
The assessment of cerebral gliomas using magnetic resonance imaging (MRI) provides
excellent structural images but cannot solve all diagnostic problems satisfactorily. The …

11C-l-Methionine Positron Emission Tomography in the Clinical Management of Cerebral Gliomas

T Singhal, TK Narayanan, V Jain, J Mukherjee… - Molecular imaging and …, 2008 - Springer
Positron emission tomography (PET) using l-[methyl-11 C]-methionine (MET) is the most
popular amino acid imaging modality in oncology, although its use is restricted to PET …

System l amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-l-tyrosine (FET)

A Habermeier, J Graf, BF Sandhöfer, JP Boissel… - Amino acids, 2015 - Springer
Abstract O-(2-fluoroethyl)-l-tyrosine (FET) labeled with fluorine-18 is an important and
specific tracer for diagnostics of glioblastoma via positron emission tomography (PET) …