Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

[HTML][HTML] Overview of the most promising radionuclides for targeted alpha therapy: The “hopeful eight”

R Eychenne, M Chérel, F Haddad, F Guérard… - Pharmaceutics, 2021 - mdpi.com
Among all existing radionuclides, only a few are of interest for therapeutic applications and
more specifically for targeted alpha therapy (TAT). From this selection, actinium-225 …

Targeted alpha therapy, an emerging class of cancer agents: a review

C Parker, V Lewington, N Shore, C Kratochwil… - JAMA …, 2018 - jamanetwork.com
Importance Targeted alpha therapy attempts to deliver systemic radiation selectively to
cancer cells while minimizing systemic toxic effects and may lead to additional treatment …

Transforming nuclear medicine with nanoradiopharmaceuticals

I Roy, S Krishnan, AV Kabashin, IN Zavestovskaya… - ACS …, 2022 - ACS Publications
Nuclear medicine is expected to make major advances in cancer diagnosis and therapy;
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …

[HTML][HTML] Targeted radionuclide therapy of human tumors

SV Gudkov, NY Shilyagina, VA Vodeneev… - International journal of …, 2015 - mdpi.com
Targeted radionuclide therapy is one of the most intensively developing directions of nuclear
medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy …

Actinium-225 for targeted α therapy: coordination chemistry and current chelation approaches

NA Thiele, JJ Wilson - Cancer biotherapy & radiopharmaceuticals, 2018 - liebertpub.com
The α-emitting radionuclide actinium-225 possesses nuclear properties that are highly
promising for use in targeted α therapy (TAT), a therapeutic strategy that employs α particle …

[HTML][HTML] Radiolabeled nanomaterial for cancer diagnostics and therapeutics: Principles and concepts

M Goel, Y Mackeyev, S Krishnan - Cancer Nanotechnology, 2023 - Springer
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …

[HTML][HTML] Radiopharmaceutical treatments for cancer therapy, radionuclides characteristics, applications, and challenges

S Salih, A Alkatheeri, W Alomaim, A Elliyanti - Molecules, 2022 - mdpi.com
Advances in the field of molecular biology have had an impact on biomedical applications,
which provide greater hope for both imaging and therapeutics. Work has been intensified on …

Imaging-guided targeted radionuclide tumor therapy: From concept to clinical translation

J Sun, Z Huangfu, J Yang, G Wang, K Hu, M Gao… - Advanced Drug Delivery …, 2022 - Elsevier
Since the first introduction of sodium iodide I-131 for use with thyroid patients almost 80
years ago, more than 50 radiopharmaceuticals have reached the markets for a wide range …

Tumor diagnosis and therapy mediated by metal phosphorus‐based nanomaterials

Y Liu, Y Wang, S Song, H Zhang - Advanced Materials, 2021 - Wiley Online Library
Metal phosphorus‐based nanomaterials (Metal‐P NMs) including metal phosphate
nanomaterials, metal phosphide nanomaterials, and metal‐black phosphorus (Metal‐BP) …