Background Auger electron emitters that can be targeted into DNA of tumour cells represent
an attractive systemic radiation therapy goal. In the situation of DNA-associated decay, the …

Neuroendocrine tumours (NETs) constitute a heterogeneous group of tumours that
frequently express cell membrane-specific peptide receptors, such as somatostatin …

The age-dependent series of stylized computational phantoms developed at the Oak Ridge
National Laboratory in the late 1970's to early 1980's has found wide applicability in …

The article reviews the background and current status of pretargeting for cancer imaging and
therapy with radionuclides. Pretargeting procedures were introduced∼ 20 years ago as an …

The transmembrane cell adhesion receptor αVβ3 integrin (αVβ3) has been identified as an
important molecular target for cancer imaging and therapy. We have developed a tetrameric …

A mathematical model based upon histological findings of cell cluster distributions in primary
breast cancers and lymph node metastases was developed. The model is unique because it …

Although systemic radionuclide therapy (SRT) is effective as a palliative therapy in patients
with metastatic cancer, there has been limited success in expanding patterns of utilization …

Radioimmunotherapy involves a form of biologically targeted radiopharmaceutical treatment
in which a radioactive isotope (typically a short-range, high-energy β-emitter) is chemically …

Radiolabelled peptides have shown to be an important class of radiopharmaceuticals for
imaging and therapy of malignancies expressing receptors of regulatory peptides. These …

Purpose: The aim of this study was to investigate the accuracy of PET‐based treatment
planning for predicting the time‐integrated activity coefficients (TIACs). Methods: The …