[HTML][HTML] Expanding theranostic radiopharmaceuticals for tumor diagnosis and therapy

C Barca, CM Griessinger, A Faust, D Depke, M Essler… - Pharmaceuticals, 2021 - mdpi.com
Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and
molecular imaging (MI), including positron emission tomography (PET), single-photon …

The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies

AR Penheiter, SJ Russell, SK Carlson - Current gene therapy, 2012 - ingentaconnect.com
Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …

[HTML][HTML] Optimizing oncolytic viral design to enhance antitumor efficacy: progress and challenges

S Chaurasiya, Y Fong, SG Warner - Cancers, 2020 - mdpi.com
The field of oncolytic virotherapy has seen remarkable advancements in last two decades,
leading to approval of the first oncolytic immuno-virotherapy, Talimogene Laherparepvec, for …

Monte Carlo simulations of absorbed dose in a mouse phantom from 18‐fluorine compounds

R Taschereau, AF Chatziioannou - Medical physics, 2007 - Wiley Online Library
The purpose of this study was to calculate internal absorbed dose distribution in mice from
preclinical small animal PET imaging procedures with fluorine‐18 labeled compounds …

Human reporter genes: potential use in clinical studies

I Serganova, V Ponomarev, R Blasberg - Nuclear medicine and biology, 2007 - Elsevier
The clinical application of positron-emission-tomography-based reporter gene imaging will
expand over the next several years. The translation of reporter gene imaging technology into …

Noninvasive molecular imaging using reporter genes

P Brader, I Serganova, RG Blasberg - Journal of Nuclear Medicine, 2013 - Soc Nuclear Med
Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …

Assessing responses to cancer therapy using molecular imaging

AA Neves, KM Brindle - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2006 - Elsevier
Tumor responses to therapy in the clinic are still evaluated primarily from non-invasive
imaging measurements of reductions in tumor size. This approach, however, lacks sensitivity …

MicroPET imaging of breast cancer using radiolabeled bombesin analogs targeting the gastrin-releasing peptide receptor

JJ Parry, R Andrews, BE Rogers - Breast cancer research and treatment, 2007 - Springer
Mammography is a well-established method for detecting primary breast cancer; however, it
has some limitations that may be overcome using nuclear imaging methods. Current …

Imaging expression of the human somatostatin receptor subtype-2 reporter gene with 68Ga-DOTATOC

H Zhang, MA Moroz, I Serganova, T Ku… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The human somatostatin receptor subtype 2 (hSSTr2)–68Ga-DOTATOC reporter system has
several attractive features for potential translation to human studies. These include a low …

Detecting tumor metastases: the road to therapy starts here

ME Menezes, SK Das, I Minn, L Emdad… - Advances in cancer …, 2016 - Elsevier
Metastasis is the complex process by which primary tumor cells migrate and establish
secondary tumors in an adjacent or distant location in the body. Early detection of metastatic …