[HTML][HTML] Expanding theranostic radiopharmaceuticals for tumor diagnosis and therapy
C Barca, CM Griessinger, A Faust, D Depke, M Essler… - Pharmaceuticals, 2021 - mdpi.com
Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and
molecular imaging (MI), including positron emission tomography (PET), single-photon …
molecular imaging (MI), including positron emission tomography (PET), single-photon …
The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies
AR Penheiter, SJ Russell, SK Carlson - Current gene therapy, 2012 - ingentaconnect.com
Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …
invasive imaging of reporter gene products to reveal the distribution of molecular …
[HTML][HTML] Optimizing oncolytic viral design to enhance antitumor efficacy: progress and challenges
The field of oncolytic virotherapy has seen remarkable advancements in last two decades,
leading to approval of the first oncolytic immuno-virotherapy, Talimogene Laherparepvec, for …
leading to approval of the first oncolytic immuno-virotherapy, Talimogene Laherparepvec, for …
Monte Carlo simulations of absorbed dose in a mouse phantom from 18‐fluorine compounds
R Taschereau, AF Chatziioannou - Medical physics, 2007 - Wiley Online Library
The purpose of this study was to calculate internal absorbed dose distribution in mice from
preclinical small animal PET imaging procedures with fluorine‐18 labeled compounds …
preclinical small animal PET imaging procedures with fluorine‐18 labeled compounds …
Human reporter genes: potential use in clinical studies
I Serganova, V Ponomarev, R Blasberg - Nuclear medicine and biology, 2007 - Elsevier
The clinical application of positron-emission-tomography-based reporter gene imaging will
expand over the next several years. The translation of reporter gene imaging technology into …
expand over the next several years. The translation of reporter gene imaging technology into …
Noninvasive molecular imaging using reporter genes
P Brader, I Serganova, RG Blasberg - Journal of Nuclear Medicine, 2013 - Soc Nuclear Med
Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …
can provide noninvasive assessments of endogenous biologic processes in living subjects …
Assessing responses to cancer therapy using molecular imaging
AA Neves, KM Brindle - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2006 - Elsevier
Tumor responses to therapy in the clinic are still evaluated primarily from non-invasive
imaging measurements of reductions in tumor size. This approach, however, lacks sensitivity …
imaging measurements of reductions in tumor size. This approach, however, lacks sensitivity …
MicroPET imaging of breast cancer using radiolabeled bombesin analogs targeting the gastrin-releasing peptide receptor
JJ Parry, R Andrews, BE Rogers - Breast cancer research and treatment, 2007 - Springer
Mammography is a well-established method for detecting primary breast cancer; however, it
has some limitations that may be overcome using nuclear imaging methods. Current …
has some limitations that may be overcome using nuclear imaging methods. Current …
Imaging expression of the human somatostatin receptor subtype-2 reporter gene with 68Ga-DOTATOC
H Zhang, MA Moroz, I Serganova, T Ku… - Journal of Nuclear …, 2011 - Soc Nuclear Med
The human somatostatin receptor subtype 2 (hSSTr2)–68Ga-DOTATOC reporter system has
several attractive features for potential translation to human studies. These include a low …
several attractive features for potential translation to human studies. These include a low …
Detecting tumor metastases: the road to therapy starts here
Metastasis is the complex process by which primary tumor cells migrate and establish
secondary tumors in an adjacent or distant location in the body. Early detection of metastatic …
secondary tumors in an adjacent or distant location in the body. Early detection of metastatic …