Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
[HTML][HTML] Molecular and functional imaging in cancer-targeted therapy: current applications and future directions
JW Bai, SQ Qiu, GJ Zhang - Signal Transduction and Targeted Therapy, 2023 - nature.com
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …
Multimodality molecular imaging of tumor angiogenesis
Molecular imaging is a key component of 21st-century cancer management. The vascular
endothelial growth factor (VEGF)/VEGF receptor signaling pathway and integrin α v β 3, a …
endothelial growth factor (VEGF)/VEGF receptor signaling pathway and integrin α v β 3, a …
PET of vascular endothelial growth factor receptor expression
For solid tumors and metastatic lesions, tumor vascularity is a critical factor in assessing
response to therapy. Here we report the first example, to our knowledge, of 64Cu-labeled …
response to therapy. Here we report the first example, to our knowledge, of 64Cu-labeled …
VEGF121-Conjugated Mesoporous Silica Nanoparticle: A Tumor Targeted Drug Delivery System
The vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling cascade
plays a critical role in tumor angiogenesis and metastasis and has been correlated with …
plays a critical role in tumor angiogenesis and metastasis and has been correlated with …
[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma
J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …
[HTML][HTML] The Role of VEGF receptors as molecular target in nuclear medicine for cancer diagnosis and combination therapy
K Masłowska, PK Halik, D Tymecka, A Misicka… - Cancers, 2021 - mdpi.com
Simple Summary The rapid development of diagnostic and therapeutic methods of the
cancer treatment causes that these diseases are becoming better known and the fight …
cancer treatment causes that these diseases are becoming better known and the fight …
How molecular imaging is speeding up antiangiogenic drug development
Drug development is a long process that generally spans about 10 to 15 years. The shift in
recent drug discovery to novel agents against specific molecular targets highlights the need …
recent drug discovery to novel agents against specific molecular targets highlights the need …
[HTML][HTML] Fusion genes altered in adult malignant gliomas
G You, X Fan, H Hu, T Jiang, CC Chen - Frontiers in Neurology, 2021 - frontiersin.org
Malignant gliomas are highly heterogeneous brain tumors in molecular genetic background.
Despite the many recent advances in the understanding of this disease, patients with adult …
Despite the many recent advances in the understanding of this disease, patients with adult …
PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide
K Hu, J Shang, L Xie, M Hanyu, Y Zhang, Z Yang… - ACS …, 2020 - ACS Publications
Vascular endothelial growth factor receptors (VEGFRs) are well recognized as significant
biomarkers of tumor angiogenesis. Herein, we have developed a first-of-its-kind peptide …
biomarkers of tumor angiogenesis. Herein, we have developed a first-of-its-kind peptide …