The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …

Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …

Cervical cancer is the third most common carcinoma in women worldwide. Despite
increasing efforts to improve therapy in this disease, a significant proportion of women still …

The clinical application of positron-emission-tomography-based reporter gene imaging will
expand over the next several years. The translation of reporter gene imaging technology into …

Metastasis is the complex process by which primary tumor cells migrate and establish
secondary tumors in an adjacent or distant location in the body. Early detection of metastatic …

Purpose: New strategies to restore sodium iodide symporter (NIS) expression and function
in radioiodine therapy–refractive anaplastic thyroid cancers (ATCs) are urgently required …

Copper is an essential cofactor for a variety of biochemical processes including oxidative
phosphorylation, cellular antioxidant activity, and elimination of free radicals. The copper …

We reported the therapeutic efficacy of 131I in hepatocellular carcinoma (HCC) cells stably
expressing the sodium iodide symporter (NIS) under the control of the tumor-specific α …

Context: We reported recently the induction of iodide accumulation in prostate cancer cells
(LNCaP) by prostate-specific antigen promoter-directed sodium iodide symporter (NIS) …

The main objective of this review is to apportion current and new insight into the
biodistribution, radiopharmacokinetics, dosimetry and cell targeting of rhenium-188 labeled …