High-Linear Energy Transfer Irradiation Targeted to Skeletal Metastases by the α-Emitter 223Ra: Adjuvant or Alternative to Conventional Modalities?

ØS Bruland, S Nilsson, DR Fisher, RH Larsen - Clinical cancer research, 2006 - AACR
The bone-seeking, α-particle-emitting radiopharmaceutical Alpharadin, 223RaCl2 (half-life=
11.4 days), is under clinical development as a novel treatment for skeletal metastases from …

Bone metastases from differentiated thyroid carcinoma

MM Muresan, P Olivier, J Leclere… - Endocrine-related …, 2008 - erc.bioscientifica.com
The presence of distant metastases from differentiated thyroid carcinoma decreases the 10-
year survival of patients by 50%. Bone metastases represent a frequent complication …

Castration-resistant prostate cancer: AUA Guideline

MS Cookson, BJ Roth, P Dahm, C Engstrom… - The Journal of …, 2013 - auajournals.org
Purpose: This Guideline is intended to provide a rational basis for the management of
patients with castration-resistant prostate cancer based on currently available published …

[HTML][HTML] Development of targeted alpha particle therapy for solid tumors

NK Tafreshi, ML Doligalski, CJ Tichacek, DN Pandya… - Molecules, 2019 - mdpi.com
Targeted alpha-particle therapy (TAT) aims to selectively deliver radionuclides emitting α-
particles (cytotoxic payload) to tumors by chelation to monoclonal antibodies, peptides or …

[HTML][HTML] Production review of accelerator-based medical isotopes

Y Wang, D Chen, R dos Santos Augusto, J Liang, Z Qin… - Molecules, 2022 - mdpi.com
The production of reactor-based medical isotopes is fragile, which has meant supply
shortages from time to time. This paper reviews alternative production methods in the form of …

[HTML][HTML] IUPAC periodic table of the elements and isotopes (IPTEI) for the education community (IUPAC Technical Report)

NE Holden, TB Coplen, JK Böhlke… - Pure and Applied …, 2018 - degruyter.com
Abstract The IUPAC (International Union of Pure and Applied Chemistry) Periodic Table of
the Elements and Isotopes (IPTEI) was created to familiarize students, teachers, and non …

Systemic metabolic radiopharmaceutical therapy in the treatment of metastatic bone pain

FM Paes, AN Serafini - Seminars in nuclear medicine, 2010 - Elsevier
Bone pain due to skeletal metastases constitutes the most common type of chronic pain
among patients with cancer. It significantly decreases the patient's quality of life and is …

[HTML][HTML] Improving quality of life in patients with advanced cancer: targeting metastatic bone pain

R von Moos, L Costa, CI Ripamonti, D Niepel… - European journal of …, 2017 - Elsevier
Metastatic bone disease in patients with advanced cancer is frequently associated with
skeletal complications. These can be debilitating, causing pain, impaired functioning and …

ICRP publication 140: radiological protection in therapy with radiopharmaceuticals

Y Yonekura, S Mattsson, G Flux, WE Bolch… - Annals of the …, 2019 - journals.sagepub.com
(1) In radiation therapy, cancer is treated to preserve life and to improve the quality of life of
the patient. While radiation therapy focuses on treating the malignancy, absorbed doses …

Options to meet the future global demand of radionuclides for radionuclide therapy

T Das, MRA Pillai - Nuclear medicine and biology, 2013 - Elsevier
Nuclear medicine continues to represent one of the important modalities for cancer
management. While diagnostic nuclear medicine for cancer management is fairly well …