Purpose This short review aims to cover the more recent and promising developments of
carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel …

Amyloid-β (Aβ) accumulation and tauopathy are considered the pathological hallmarks of
Alzheimer's disease (AD), but attenuation in choline signaling, including decreased nicotinic …

Purpose To clarify whether changes in the cholinergic transmission occur early in the course
of Alzheimer's disease (AD), we carried out positron emission tomography (PET) with the …

Cholinergic receptors represent a promising class of diagnostic and therapeutic targets due
to their significant involvement in cognitive decline associated with neurological disorders …

The increasing application of positron emission tomography (PET) in nuclear medicine has
stimulated the extensive development of a multitude of new radiotracers and novel …

In vivo molecular imaging is the visualization, characterization, and measurement of
biological processes at the molecular and cellular levels in humans and other living …

In addition to being a powerful clinical tool, Positron emission tomography (PET) is also
used in small laboratory animal research to visualize and track certain molecular processes …

Radiochemistry with the short-lived positron emitter 11 C (half-life 20.38 min) represents
special challenges in terms of synthesis time and labeling techniques. The recent …

The Pd (0)-mediated rapid coupling of methyl iodide with an excess of
alkenyltributylstannane was examined with the aim of incorporating a short-lived 11C …

OBJECTIVE: The main aim of this work is to describe the fundamental aspects of the
psychopharmacology of nicotine, in order to understand the addictive properties peculiar to …