Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Noninvasive cell-tracking methods

MF Kircher, SS Gambhir, J Grimm - Nature reviews Clinical oncology, 2011 - nature.com
Cell-based therapies, such as adoptive immunotherapy and stem-cell therapy, have
received considerable attention as novel therapeutics in oncological research and clinical …

Monitoring of bone marrow cell homing into the infarcted human myocardium

M Hofmann, KC Wollert, GP Meyer, A Menke… - Circulation, 2005 - Am Heart Assoc
Background—Intracoronary transfer of autologous bone marrow cells (BMCs) promotes
recovery of left ventricular systolic function in patients with acute myocardial infarction …

Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction

DL Kraitchman, M Tatsumi, WD Gilson, T Ishimori… - Circulation, 2005 - Am Heart Assoc
Background—Recent results from animal studies suggest that stem cells may be able to
home to sites of myocardial injury to assist in tissue regeneration. However, the histological …

Assessment and optimization of cell engraftment after transplantation into the heart

JV Terrovitis, RR Smith, E Marbán - Circulation research, 2010 - Am Heart Assoc
Myocardial regeneration using stem and progenitor cell transplantation in the injured heart
has recently become a major goal in the treatment of cardiac disease. Experimental studies …

Stem cell therapy for ischemic heart diseases

H Yu, K Lu, J Zhu, J Wang - British medical bulletin, 2017 - academic.oup.com
Introduction Ischemic heart diseases, especially the myocardial infarction, is a major hazard
problem to human health. Despite substantial advances in control of risk factors and …

Clinical imaging in regenerative medicine

AV Naumova, M Modo, A Moore, CE Murry… - Nature …, 2014 - nature.com
In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …

[HTML][HTML] Regenerative medicine for the treatment of ischemic heart disease; status and future perspectives

B Arjmand, M Abedi, M Arabi… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular disease is now the leading cause of adult death in the world. According to
new estimates from the World Health Organization, myocardial infarction (MI) is responsible …

Homing and engraftment of progenitor cells: a prerequisite for cell therapy

E Chavakis, C Urbich, S Dimmeler - Journal of molecular and cellular …, 2008 - Elsevier
Cell therapy is a promising therapeutic option for treating patients with ischemic diseases.
The efficiency of cell therapy to augment recovery after ischemia depends on the sufficient …

[HTML][HTML] Mending a broken heart: current strategies and limitations of cell-based therapy

LC Liew, BX Ho, BS Soh - Stem Cell Research & Therapy, 2020 - Springer
The versatility of pluripotent stem cells, attributable to their unlimited self-renewal capacity
and plasticity, has sparked a considerable interest for potential application in regenerative …