The role of neuroimaging in Parkinson's disease

NSR Bidesi, I Vang Andersen… - Journal of …, 2021 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of people
worldwide. Two hallmarks of PD are the accumulation of alpha‐synuclein and the loss of …

The role of dopaminergic imaging in patients with symptoms of dopaminergic system neurodegeneration

JL Cummings, C Henchcliffe, S Schaier, T Simuni… - Brain, 2011 - academic.oup.com
Diagnosis of neurological and psychiatric conditions associated with disturbances of
dopaminergic functioning can be challenging, especially in the early stages, and may be …

Abnormal metabolic network activity in Parkinson's disease: test—retest reproducibility

Y Ma, C Tang, PG Spetsieris… - Journal of Cerebral …, 2007 - journals.sagepub.com
Parkinson's disease (PD) is associated with an abnormal pattern of regional brain function.
The expression of this PD-related covariance pattern (PDRP) has been used to assess …

Imaging in Parkinson's disease: the role of monoamines in behavior

DJ Brooks, P Piccini - Biological psychiatry, 2006 - Elsevier
Positron emission tomography (PET) and single photon emission computed tomography
(SPECT) can measure striatal dopamine (DA) terminal function in vivo as reflected by DA …

Clinical testing of an optimized software solution for an automated, observer-independent evaluation of dopamine transporter SPECT studies

W Koch, PE Radau, C Hamann… - Journal of Nuclear …, 2005 - Soc Nuclear Med
A lack of standardized evaluation procedures for dopamine transporter (DAT) SPECT
investigations impairs both intra-and interindividual comparisons as well as multicenter trials …

Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers—a SPECT study

PS Chen, YK Yang, TL Yeh, IH Lee, WJ Yao, NT Chiu… - Neuroimage, 2008 - Elsevier
Recent lines of research suggest that, in addition to hypothalamic sites, the striatum
dopaminergic system may be a target for regulating homeostasis that may be represented …

Oxytocin receptor gene rs53576 polymorphism modulates oxytocin–dopamine interaction and neuroticism traits—a SPECT study

WH Chang, IH Lee, KC Chen, MH Chi, NT Chiu… - …, 2014 - Elsevier
Brain oxytocin and dopamine systems interact to modulate social cognitive behavior.
Whether the interactions are modulated by oxytocin receptor (OXTR) gene variations …

[HTML][HTML] Dysregulation of oxytocin and dopamine in the corticostriatal circuitry in bipolar II disorder

SY Wei, HH Tseng, HH Chang, TH Lu… - Translational …, 2020 - nature.com
The oxytocin (OXT) and dopamine systems synergistically facilitate striatal reactivity.
Abnormal striatal activation has repeatedly been observed in patients with bipolar disorder …

Dopamine transporter availability in medication free and in bupropion treated depression: a 99mTc-TRODAT-1 SPECT study

M Árgyelán, Z Szabó, B Kanyó, A Tanács… - Journal of affective …, 2005 - Elsevier
BACKGROUND: Bupropion is thought to exert its antidepressive effect by blocking the
dopamine transporter (DAT). The purpose of this study was to evaluate the DAT activity in …

[HTML][HTML] Salivary DJ-1 could be an indicator of Parkinson's disease progression

WY Kang, Q Yang, XF Jiang, W Chen… - Frontiers in aging …, 2014 - frontiersin.org
Objective: The goal of the current investigation was to explore whether salivary DJ-1 could
be a potential biomarker for monitoring disease progression in Parkinson's disease (PD) by …