[HTML][HTML] Fluorinated carbohydrates for 18 F-positron emission tomography (PET)

E Campbell, C Jordan, R Gilmour - Chemical Society Reviews, 2023 - pubs.rsc.org
Carbohydrate diversity is foundational in the molecular literacy that regulates cellular
function and communication. Consequently, delineating and leveraging this structure …

[HTML][HTML] Positron emission tomography (PET) imaging with 18F-based radiotracers

MM Alauddin - American journal of nuclear medicine and …, 2012 - ncbi.nlm.nih.gov
Abstract Positron Emission Tomography (PET) is a nuclear medicine imaging technique that
is widely used in early detection and treatment follow up of many diseases, including cancer …

Mesenchymal Stem Cell Targeting of Microscopic Tumors and Tumor Stroma Development Monitored by Noninvasive In vivo Positron Emission Tomography Imaging

SC Hung, WP Deng, WK Yang, RS Liu, CC Lee… - Clinical cancer …, 2005 - AACR
The aim of this study was to assess the efficacy human mesenchymal stem cells (hMSC) for
targeting microscopic tumors and suicide gene or cytokine gene therapy. Immunodeficient …

The progress and promise of molecular imaging probes in oncologic drug development

GJ Kelloff, KA Krohn, SM Larson, R Weissleder… - Clinical Cancer …, 2005 - AACR
As addressed by the recent Food and Drug Administration Critical Path Initiative, tools are
urgently needed to increase the speed, efficiency, and cost-effectiveness of drug …

Recent advances in the synthesis of fluorinated nucleosides

XL Qiu, XH Xu, FL Qing - Tetrahedron, 2010 - Elsevier
Fluorine is one of the most abundant elements on earth. However, it occurs extremely rarely
in biological compounds. Due to the specific properties of fluorine atom (s), including small …

Molecular imaging of prostate cancer: PET radiotracers

H Jadvar - American Journal of Roentgenology, 2012 - Am Roentgen Ray Soc
OBJECTIVE. Recent advances in the fundamental understanding of the complex biology of
prostate cancer have provided an increasing number of potential targets for imaging and …

Strategies for the synthesis of fluorinated nucleosides, nucleotides and oligonucleotides

H Shet, R Sahu, YS Sanghvi, AR Kapdi - The Chemical Record, 2022 - Wiley Online Library
Fluorinated nucleosides and oligonucleotides are of specific interest as probes for studying
nucleic acids interaction, structures, biological transformations, and its biomedical …

Unique role of molecular imaging probes for viral infection

S Liu, T Liu, W Tian, Q Zhang, Z Wang, X Hou… - TrAC Trends in …, 2023 - Elsevier
In recent years, several epidemics, such as COVID-19 and other viral infections, have been
attacking human health and affecting the economy. Non-invasively detecting virus entry into …

Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU

S Soghomonyan, A Hajitou, R Rangel, M Trepel… - Nature protocols, 2007 - nature.com
Non-invasive imaging of transgene expression requires the appropriate combination of a
reporter gene and a reporter probe.[18F] FEAU positron emission tomography (PET) is used …

Gene therapy imaging in patients for oncological applications

I Peñuelas, U Haberkorn, S Yaghoubi… - European journal of …, 2005 - Springer
Thus far, traditional methods for evaluating gene transfer and expression have been shown
to be of limited value in the clinical arena. Consequently there is a real need to develop new …