Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its
association with an aggressive tumour phenotype and therapeutic resistance. Given its …

Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …

The imaging and clinical management of patients with brain tumor continue to evolve over
time and now heavily rely on physiologic imaging in addition to high-resolution structural …

Malignant gliomas and metastatic tumors are the most common brain tumors. Neuroimaging
plays a significant role clinically. In low-grade tumors, neuroimaging is needed to evaluate …

Neuroimaging enables the noninvasive evaluation of glioma and is considered to be one of
the key factors for individualized therapy and patient management, since accurate diagnosis …

Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors.
Pretherapy planning and posttreatment response assessments rely heavily on gadolinium …

Purpose Hypoxia is a condition of insufficient oxygen to support metabolism which occurs
when the vascular supply is interrupted, or when a tumour outgrows its vascular supply. It is …

Hypoxia is implicated in many aspects of tumor development, angiogenesis, and growth in
many different tumors. Brain tumors, particularly the highly aggressive glioblastoma …

The importance of hypoxia in disease pathogenesis and prognosis is gathering increasing
clinical significance and having a greater impact on patient management and outcome …