Pd-l1-targeted radionuclide therapy combined with αpd-l1 antibody immunotherapy synergistically improves the antitumor effect
X Wen, X Zeng, X Cheng, X Zeng, J Liu… - Molecular …, 2022 - ACS Publications
Immune checkpoint blockers (ICBs) targeting programmed death receptor 1 (PD-1) ligand 1
(PD-L1) for immunotherapy have radically reformed oncology. It is of great significance to …
(PD-L1) for immunotherapy have radically reformed oncology. It is of great significance to …
Differential tumor cell targeting of anti-HER2 (HerceptinŽ) and anti-CD20 (MabtheraŽ) coupled nanoparticles
A Cirstoiu-Hapca, L Bossy-Nobs, F Buchegger… - International journal of …, 2007 - Elsevier
Two types of antibody-labeled nanoparticles (mAb-NPs) were prepared with the aim to
achieve specific tumor targeting. Anti-HER2 and anti-CD20 monoclonal antibodies (mAb) …
achieve specific tumor targeting. Anti-HER2 and anti-CD20 monoclonal antibodies (mAb) …
Porous hollow palladium nanoplatform for imaging-guided trimodal chemo-, photothermal-, and radiotherapy
Cancer is one of the major causes of human death. There are many types of cancer
treatment including surgery, chemotherapy, radiotherapy, and photothermal therapy …
treatment including surgery, chemotherapy, radiotherapy, and photothermal therapy …
Nanomedicines for active targeting: physico-chemical characterization of paclitaxel-loaded anti-HER2 immunonanoparticles and in vitro functional studies on target …
A Cirstoiu-Hapca, F Buchegger, L Bossy… - European Journal of …, 2009 - Elsevier
Paclitaxel (Tx)-loaded anti-HER2 immunonanoparticles (NPs-Tx-HER) were prepared by the
covalent coupling of humanized monoclonal anti-HER2 antibodies (trastuzumab …
covalent coupling of humanized monoclonal anti-HER2 antibodies (trastuzumab …
[HTML][HTML] 99mTc-labeled Rituximab for Imaging B Lymphocyte Infiltration in Inflammatory Autoimmune Disease Patients
Purpose The rationale of the present study was to radiolabel rituximab with 99m-technetium
and to image B lymphocytes infiltration in the affected tissues of patients with chronic …
and to image B lymphocytes infiltration in the affected tissues of patients with chronic …
Regional Radiochemotherapy Using In Situ Hydrogel
A Azhdarinia, DJ Yang, DF Yu, R Mendez, C Oh… - Pharmaceutical …, 2005 - Springer
Purpose. To evaluate the feasibility of regional radiochemotherapy of mammary tumors
using in situ hydrogel loaded with cisplatin (CDDP) and rhenium-188 (188 Re). Methods …
using in situ hydrogel loaded with cisplatin (CDDP) and rhenium-188 (188 Re). Methods …
Preparation and preclinical evaluation of 131I‐trastuzumab for breast cancer
M Kameswaran, V Gota, R Ambade… - Journal of Labelled …, 2017 - Wiley Online Library
Trastuzumab that targets the human epidermal growth factor receptor type 2 (HER2) is
known to benefit patients with HER2+ metastatic breast cancer. The objective was to explore …
known to benefit patients with HER2+ metastatic breast cancer. The objective was to explore …
131I-Nimotuzumab–A potential radioimmunotherapeutic agent in treatment of tumors expressing EGFR
M Kameswaran, G Samuel, HD Sarma… - Applied Radiation and …, 2015 - Elsevier
The anti-EGFR antibody Nimotuzumab was radioiodinated with I-131 by Chloramine T and
Iodogen methods. The 131 I-Nimotuzumab was purified and characterized by HPLC …
Iodogen methods. The 131 I-Nimotuzumab was purified and characterized by HPLC …
[HTML][HTML] Long-term complete responses after 131I-tositumomab therapy for relapsed or refractory indolent non-Hodgkin's lymphoma
F Buchegger, C Antonescu, AB Delaloye, C Helg… - British journal of …, 2006 - nature.com
We present the long-term results of 18 chemotherapy relapsed indolent (N= 12) or
transformed (N= 6) NHL patients of a phase II anti-CD20 131 I-tositumomab (BexxarŽ) …
transformed (N= 6) NHL patients of a phase II anti-CD20 131 I-tositumomab (BexxarŽ) …
Efficacy of nimotuzumab (hR3) conjugated with 131I or 90Y in laryngeal carcinoma xenograft mouse model
Purpose The humanized monoclonal antibody hR3, both alone and in combination with
other chemotherapeutic agents and radiotherapy, can be used to treat head and neck …
other chemotherapeutic agents and radiotherapy, can be used to treat head and neck …