Molecular-genetic imaging based on reporter gene expression

JH Kang, JK Chung - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Molecular imaging includes proteomic, metabolic, cellular biologic process, and genetic
imaging. In a narrow sense, molecular imaging means genetic imaging and can be called …

Norepinephrine transporter as a target for imaging and therapy

N Pandit-Taskar, S Modak - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
The norepinephrine transporter (NET) is essential for norepinephrine uptake at the synaptic
terminals and adrenal chromaffin cells. In neuroendocrine tumors, NET can be targeted for …

The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies

AR Penheiter, SJ Russell, SK Carlson - Current gene therapy, 2012 - ingentaconnect.com
Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …

Radiolabeled metaiodobenzylguanidine for the treatment of neuroblastoma

SG DuBois, KK Matthay - Nuclear medicine and biology, 2008 - Elsevier
INTRODUCTION: Neuroblastoma is the most common pediatric extracranial solid cancer.
This tumor is characterized by metaiodobenzylguanidine (MIBG) avidity in 90% of cases …

[HTML][HTML] Multimodality reporter gene imaging: Construction strategies and application

M Li, Y Wang, M Liu, X Lan - Theranostics, 2018 - ncbi.nlm.nih.gov
Molecular imaging has played an important role in the noninvasive exploration of multiple
biological processes. Reporter gene imaging is a key part of molecular imaging. By …

[BOOK][B] Molecular imaging: basic principles and applications in biomedical research

M Rudin - 2013 - books.google.com
The area of molecular imaging has matured over the past decade and is still growing
rapidly. Many concepts developed for molecular biology and cellular imaging have been …

Human reporter genes: potential use in clinical studies

I Serganova, V Ponomarev, R Blasberg - Nuclear medicine and biology, 2007 - Elsevier
The clinical application of positron-emission-tomography-based reporter gene imaging will
expand over the next several years. The translation of reporter gene imaging technology into …

Noninvasive molecular imaging using reporter genes

P Brader, I Serganova, RG Blasberg - Journal of Nuclear Medicine, 2013 - Soc Nuclear Med
Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …

[HTML][HTML] Evaluation of norepinephrine transporter expression and metaiodobenzylguanidine avidity in neuroblastoma: a report from the Children's Oncology Group

SG DuBois, E Geier, V Batra, SW Yee… - International journal of …, 2012 - hindawi.com
Purpose. 123 I-metaiodobenzylguanidine (MIBG) is used for the diagnostic evaluation of
neuroblastoma. We evaluated the relationship between norepinephrine transporter (NET) …

Current progress and future challenges in the biochemical diagnosis and treatment of pheochromocytomas and paragangliomas

G Eisenhofer, G Siegert, J Kotzerke… - Hormone and …, 2008 - thieme-connect.com
Findings from five independent studies-with close to 350 patients with pheochromocytoma
and more than 2 500 in whom the tumor was excluded-indicate that measurements of …