The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Distant organ metastasis is the most important factor in determining patient survival in
cancer. This is thought to occur via the body's own systems for transporting fluid and cells …

In 2008, a proposal for assessing the risk of induction of skin sensitization to fragrance
materials Quantitative Risk Assessment 1 (QRA1) was published. This was implemented for …

Objective: The objective of this study was to evaluate, in an international multicenter phase
III trial, the accuracy, use, and morbidity of intraoperative lymphatic mapping and sentinel …

Highlights•A melanoma consensus conference, organised by the ESMO Guidelines
Committee, was attended by 32 experts from 14 countries•The experts compiled …

The coronavirus disease 2019 (COVID-19) pandemic has dominated nearly everyone's life
since its initial outbreak in the Hubei province of China in December 2019. The disease had …

Hollow microneedles can help overcome the skin permeation barrier imposed by the stratum
corneum and facilitate transcutaneous delivery of nanoparticle delivery systems. In the …

Background Variations in arm lymphatic drainage put the arm lymphatics at risk for
disruption during axillary lymph node surgery. Mapping the drainage of the arm with blue …

Purpose Sentinel lymph node biopsy is an essential staging tool in patients with clinically
localized melanoma. The harvesting of a sentinel lymph node entails a sequence of …

While the lymphatic system is increasingly associated with diseases of prevalence, study of
these diseases is difficult owing to the paucity of imaging techniques with the sensitivity and …