Role of apoptosis in reperfusion injury

F Eefting, B Rensing, J Wigman… - Cardiovascular …, 2004 - academic.oup.com
Many changes occur during reperfusion of the myocardium after ischemic damage. Necrosis
and apoptosis appear to be ongoing during ischemia, while apoptosis is boosted by the …

Past, present, and future of annexin A5: from protein discovery to clinical applications

HH Boersma, BLJH Kietselaer, LML Stolk… - Journal of nuclear …, 2005 - Soc Nuclear Med
In this article, we review the clinical aspects of imaging with the programmed cell–detecting
protein annexin A5 (anxA5). AnxA5 binds to phosphatidylserine, which is one of the “eat me” …

Detecting retinal cell stress and apoptosis with DARC: Progression from lab to clinic

MF Cordeiro, D Hill, R Patel, P Corazza… - Progress in Retinal and …, 2022 - Elsevier
Abstract DARC (Detection of Apoptosing Retinal Cells) is a retinal imaging technology that
has been developed within the last 2 decades from basic laboratory science to Phase 2 …

In vivo detection of apoptosis

FG Blankenberg - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
After several decades of debate, it is now widely acknowledged that apoptosis, also known
as programmed cell death, is central to homoeostasis and normal development and …

Oxidative stress-elicited myocardial apoptosis during reperfusion

ZQ Zhao - Current opinion in pharmacology, 2004 - Elsevier
Myocardial apoptosis primarily triggered during reperfusion has been associated with
cardiac dysfunction and extension of infarction. Although potential signaling pathways …

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto‐optical nanoparticle

DE Sosnovik, EA Schellenberger… - … in Medicine: An …, 2005 - Wiley Online Library
The ability to image cardiomyocyte apoptosis in vivo with high‐resolution MRI could facilitate
the development of novel cardioprotective therapies. The sensitivity of the novel …

Apoptosis-detecting radioligands: current state of the art and future perspectives

CMM Lahorte, JL Vanderheyden, N Steinmetz… - European journal of …, 2004 - Springer
This review provides a critical and thorough overview of the radiopharmaceutical
development and in vivo evaluation of all apoptosis-detecting radioligands that have …

[HTML][HTML] Therapeutic potential of annexins in sepsis and COVID-19

L Mui, CM Martin, BJ Tschirhart, Q Feng - Frontiers in Pharmacology, 2021 - frontiersin.org
Sepsis is a continuing problem in modern healthcare, with a relatively high prevalence, and
a significant mortality rate worldwide. Currently, no specific anti-sepsis treatment exists …

[HTML][HTML] New SPECT and PET radiopharmaceuticals for imaging cardiovascular disease

OO Sogbein, M Pelletier-Galarneau… - BioMed research …, 2014 - hindawi.com
Nuclear cardiology has experienced exponential growth within the past four decades with
converging capacity to diagnose and influence management of a variety of cardiovascular …

In vivo imaging of radiation-induced apoptosis in follicular lymphoma patients

RLM Haas, D de Jong, RAV Olmos… - International Journal of …, 2004 - Elsevier
PURPOSE: To evaluate 99mTc-Annexin-V (TAV) scintigraphy in monitoring radiation-
induced apoptotic cell death in follicular lymphoma (FL) patients. PATIENTS AND …