Biomarkers in cancer staging, prognosis and treatment selection

JA Ludwig, JN Weinstein - Nature Reviews Cancer, 2005 - nature.com
Advances in genomics, proteomics and molecular pathology have generated many
candidate biomarkers with potential clinical value. Their use for cancer staging and …

Monoclonal versus polyclonal antibodies: distinguishing characteristics, applications, and information resources

NS Lipman, LR Jackson, LJ Trudel… - ILAR journal, 2005 - academic.oup.com
Antibodies are host proteins that comprise one of the principal effectors of the adaptive
immune system. Their utility has been harnessed as they have been and continue to be …

[BOOK][B] Handbook of radiotherapy physics: theory and practice

P Mayles, A Nahum, JC Rosenwald - 2007 - taylorfrancis.com
From background physics and biological models to the latest imaging and treatment
modalities, the Handbook of Radiotherapy Physics: Theory and Practice covers all …

Tumor imaging using a picomolar affinity HER2 binding affibody molecule

A Orlova, M Magnusson, TLJ Eriksson, M Nilsson… - Cancer research, 2006 - AACR
The detection of cell-bound proteins that are produced due to aberrant gene expression in
malignant tumors can provide important diagnostic information influencing patient …

Nanotechnological applications in medicine

SD Caruthers, SA Wickline, GM Lanza - Current opinion in Biotechnology, 2007 - Elsevier
Nanotechnology-based tools and techniques are rapidly emerging in the fields of medical
imaging and targeted drug delivery. Employing constructs such as dendrimers, liposomes …

A highly specific multiple enhancement theranostic nanoprobe for PET/MRI/PAI image‐guided radioisotope combined photothermal therapy in prostate cancer

L Xia, X Meng, L Wen, N Zhou, T Liu, X Xu, F Wang… - Small, 2021 - Wiley Online Library
An integrated molecular probe for combined tumor‐targeted multimodal imaging and
therapy in the era of precision medicine requires a multiplexed platform that simultaneously …

Fluorescent peptide probes for in vivo diagnostic imaging

CH Tung - Peptide Science: Original Research on …, 2004 - Wiley Online Library
Recently, many novel peptide‐based near‐infrared (NIR) fluorescent molecular probes have
been developed for in vivo biomedical imaging. To report specific information of biological …

Molecular imaging and therapy of atherosclerosis with targeted nanoparticles

SA Wickline, AM Neubauer, PM Winter… - Journal of Magnetic …, 2007 - Wiley Online Library
Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis
and therapy for decades to come. This review seeks to illustrate selected examples of newly …

Arylfluoroborates and Alkylfluorosilicates as Potential PET Imaging Agents:  High-Yielding Aqueous Biomolecular 18F-Labeling

R Ting, MJ Adam, TJ Ruth… - Journal of the American …, 2005 - ACS Publications
Organometalloid compositions of silicon and boron permit rapid, high-yielding, one-step
radiolabeling of a covalently linked protein ligand (biotin) under aqueous conditions to give …

Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors

A Orlova, V Tolmachev, R Pehrson, M Lindborg, T Tran… - Cancer research, 2007 - AACR
Abstract The Affibody molecule ZHER2: 342-pep2, site-specifically and homogeneously
conjugated with a 1, 4, 7, 10-tetra-azacylododecane-N, N′, N ″, N‴-tetraacetic acid …