Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

Abstract Cluster of differentiation-44 (CD44) is a ubiquitously present glycoprotein on the
surface of mammalian cells that plays a significant role in a number of biological functions …

CD44, a cell-surface glycoprotein, has long been studied as a cancer molecule due to its
essential role in physiological activities in normal cells and pathological activities in cancer …

CD44 is a family of single-span transmembrane glycoproteins. Members of this family differ
in the extracellular domain where ten variant exons are either excluded or included in …

Triple-negative breast cancer (TNBC) is one of the most lethal subtypes of breast cancer that
has limited treatment options. Its high rates of recurrence and metastasis have been …

Targeted therapies are the state of the art in oncology today, and every year new Tumor-
associated antigens (TAAs) are developed for preclinical research and clinical trials, but few …

Head and neck squamous cell carcinoma (HNSCC) is an often highly invasive tumor,
infiltrating functionally important tissue areas. Achieving complete tumor resection and …

The efficacy of external beam radiotherapy (EBRT) is dose dependent, but the dose that can
be applied to solid tumour lesions is limited by the sensitivity of the surrounding tissue. The …

Prostate cancer (CaP) is a major health problem in males in Western countries. Current
therapeutic approaches are limited and many patients die of secondary disease …

Head and neck squamous cell carcinoma (HNSCC) is a common and severe cancer with
low survival rate in advanced stages. Noninvasive imaging of prognostic and therapeutic …