This article presents a general discussion on what has been achieved so far and on the
possible future developments of targeted alpha (α)-particle therapy (TAT). Clinical …

The purpose of the EANM Dosimetry Committee is to provide recommendations and
guidance to scientists and clinicians on patient-specific dosimetry. Radiopharmaceuticals …

Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However,
in order to deliver the required dose to the tumor, minimize potential toxicity in normal …

Abstract BACKGROUND: 177Lu‐(DOTA0, Tyr3) octreotate is a new treatment modality for
disseminated neuroendocrine tumors. According to a consensus protocol, the calculated …

Tumor dosimetry was performed for 177Lu-DOTATATE with the aims of better understanding
the range and variation of the tumor-absorbed doses (ADs), how different dosimetric …

Abstract Background Recently, 177 Lu-dotatate therapy for neuroendocrine tumours has
received regulatory approval. Dosimetry can be used to optimize treatment on an individual …

Abstract Background Somatostatin receptor 68Ga PET imaging is standard for evaluation of
a patient's suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine …

This paper presents a systematic analysis of the inherent uncertainty in internal dose
calculations for radiopharmaceuticals. A generic equation for internal dose is presented, and …

Targeted radionuclide therapy (TRT) is an increasingly used treatment modality for a range
of cancers. To date, few treatments have involved the use of dosimetry either to plan …

In SPECT imaging of pure beta emitters, such as 90 Y, the acquired spectrum is very
complex, which increases the demands on the imaging protocol and the reconstruction. In …