Clinical controversies in aerosol therapy for infants and children

RM DiBlasi - Respiratory Care, 2015 - rc.rcjournal.com
Pediatric patients are different from adult patients with respect to airway anatomy and
breathing patterns. They are also incapable of following commands and often reject …

Respiratory syncytial virus: diagnosis, treatment and prevention

LS Eiland - The Journal of Pediatric Pharmacology and …, 2009 - meridian.allenpress.com
Respiratory Syncytial Virus (RSV) is a common virus that infects children and adults;
however, children younger than two years of age tend to develop more serious respiratory …

[HTML][HTML] Comparison of aerosol delivery across combinations of drug delivery interfaces with and without concurrent high-flow nasal therapy

G Bennett, M Joyce, EF Fernández… - Intensive care medicine …, 2019 - Springer
Background Current clinical practice during high-flow nasal therapy (HFNT) involves
utilization of a nasal cannula to provide humidification, with a facemask placed over the …

The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial

J Teunissen, AHJ Hochs… - European …, 2014 - Eur Respiratory Soc
Bronchiolitis is a common disorder in young children that often results in hospitalisation.
Except for a possible effect of nebulised hypertonic saline (sodium chloride), no evidence …

Aerosol delivery to ventilated infant and pediatric patients

JB Fink - Respiratory care, 2004 - rc.rcjournal.com
Infants have low tidal volume, vital capacity, and functional residual capacity, and short
respiratory cycles (low I: E ratio), which result in a low residence time for aerosol particles …

Incorporating a nebulizer system into high-flow nasal cannula improves comfort in infants with bronchiolitis

J Valencia-Ramos, A Mirás, A Cilla, C Ochoa… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: High-flow nasal cannula (HFNC) is increasingly used to provide respiratory
support in infants with bronchiolitis. The delivery of aerosol therapy through a jet nebulizer is …

Delivery of inhalation drugs to children for asthma and other respiratory diseases

PCL Kwok, HK Chan - Advanced drug delivery reviews, 2014 - Elsevier
Infants and children constitute a patient group that has unique requirements in pulmonary
drug delivery. Since their lungs develop continuously until they reach adulthood, the airways …

Nebuliser hood compared to mask in wheezy infants: aerosol therapy without tears!

I Amirav, I Balanov, M Gorenberg, D Groshar… - Archives of disease in …, 2003 - adc.bmj.com
Background: Small volume nebulisers (SVNs) with masks commonly provide aerosol
therapy for infants with lung diseases. However, infants and toddlers are often disturbed by …

In Vitro Analysis of Nasal Interface Options for High-Efficiency Aerosol Administration to Preterm Infants

C Howe, MAM Momin, K Bass, G Aladwani… - Journal of Aerosol …, 2022 - liebertpub.com
Background: An infant air-jet dry powder inhaler (DPI) platform has recently been developed
that in combination with highly dispersible spray-dried powder formulations can achieve …

Factors that affect the efficacy of inhaled corticosteroids for infants and young children

I Amirav, MT Newhouse, S Minocchieri… - Journal of Allergy and …, 2010 - Elsevier
Infants (0–1 years of age) and young children (1–3 years of age) are a unique
subpopulation with regard to inhaled therapies. There are various anatomic, physiological …