Prostate cancer (PCA) is the second most common tumour in men worldwide. Whereas
prostate specific antigen (PSA) is an established biochemical marker, the optimal imaging …

Cancer cells hijack metabolic pathways to support bioenergetics and biosynthetic
requirements for their uncontrolled growth. Thus, cancer can be considered as a metabolic …

Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …

The ability of 11C-choline and multimodality fusion imaging with integrated PET and contrast-
enhanced CT (PET/CT) was investigated to delineate prostate carcinoma (PCa) within the …

Rationale: The evaluation of the efficacy of the treatment of men with prostate cancer is
largely based on post treatment levels of PSA. An increase in PSA or biochemical …

Purpose: Prostate stem cell antigen (PSCA) is a cell surface glycoprotein that is
overexpressed in prostate cancer, including hormone refractory disease. Previous …

Purpose The aim of the study was to assess the utility of 18 F-fluorocholine (FCH), compared
to standard imaging of bone scan (BS) and contrast-enhanced abdominopelvic computed …

18F-FDG is in widespread use in cancer imaging but has limited utility in staging and
monitoring of prostate cancer. 1-11C-Labeled acetate, a substrate for the citric acid cycle, is …

Objective: The elevated choline transporters (ChT), choline kinase (ChK), choline uptake,
and phosphorylation in certain tumor cells have influenced the development of radiolabeled …

We hypothesized that the glucose metabolism of prostate cancer is modulated by androgen.
We performed in vivo biodistribution and imaging studies of [F-18] fluorodeoxyglucose …