Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography

BM Zeglis, JS Lewis - Dalton Transactions, 2011 - pubs.rsc.org
Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …

A biomimetic approach for enhancing the in vivo half-life of peptides

SC Penchala, MR Miller, A Pal, J Dong… - Nature chemical …, 2015 - nature.com
The tremendous therapeutic potential of peptides has not yet been realized, mainly owing to
their short in vivo half-life. Although conjugation to macromolecules has been a mainstay …

SPECT/CT in tumor imaging: technical aspects and clinical applications

Z Keidar, O Israel, Y Krausz - Seminars in nuclear medicine, 2003 - Elsevier
Diagnostic imaging has gained a major role in the management of patients with cancer and
has made a further step forward with the introduction of fusion techniques into the field. This …

Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS

F Rösch, RP Baum - Dalton transactions, 2011 - pubs.rsc.org
Generator-derived radionuclides for PET/CT imaging are promising for optimizing targeted
radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation …

H4octapa: An Acyclic Chelator for 111In Radiopharmaceuticals

EW Price, JF Cawthray, GA Bailey… - Journal of the …, 2012 - ACS Publications
This preliminary investigation of the octadentate acyclic chelator H4octapa (N4O4) with
111In/115In3+ has demonstrated it to be an improvement on the shortcomings of the current …

[HTML][HTML] Radiometals in Imaging and Therapy: Highlighting Two Decades of Research

S Sharma, MK Pandey - Pharmaceuticals, 2023 - mdpi.com
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

[HTML][HTML] Radionuclide generators: The prospect of availing PET radiotracers to meet current clinical needs and future research demands

A Dash, R Chakravarty - American journal of nuclear medicine and …, 2019 - ncbi.nlm.nih.gov
Targeted molecular imaging with positron emission tomography (PET) constitutes a
successful technique for detecting and diagnosing disease conditions promptly and …

Radionuclide candidates for β+ γ coincidence PET: an overview

M Sitarz, JP Cussonneau, T Matulewicz… - Applied Radiation and …, 2020 - Elsevier
Following the advancement of the Positron Emission Tomography (PET), a novel technique
emerged which takes advantage of the gamma quanta emitted, in some cases, after the β+ …