Use of PET for monitoring cancer therapy and for predicting outcome

WA Weber - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
PET with the glucose analog 18F-FDG is increasingly used to monitor tumor response in
patients undergoing chemotherapy and chemoradiotherapy. Numerous studies have shown …

Brain tumors

K Herholz, KJ Langen, C Schiepers… - Seminars in nuclear …, 2012 - Elsevier
This review addresses the specific contributions of nuclear medicine techniques, and
especially positron emission tomography (PET), for diagnosis and management of brain …

Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated …

AL Grosu, WA Weber, M Franz, S Stärk, M Piert… - International Journal of …, 2005 - Elsevier
Purpose: To develop a valid treatment strategy for recurrent high-grade gliomas using
stereotactic hypofractionated reirradiation based on biologic imaging and temozolomide …

An interindividual comparison of O-(2-[18F] Fluoroethyl)-L-Tyrosine (FET)–and L-[Methyl-11C] methionine (MET)–PET in patients with brain gliomas and metastases

AL Grosu, ST Astner, E Riedel, C Nieder… - International Journal of …, 2011 - Elsevier
PURPOSE: L-[methyl-11C] methionine (MET)–positron emission tomography (PET) has a
high sensitivity and specificity for imaging of gliomas and metastatic brain tumors. The short …

L-(methyl-11C) methionine positron emission tomography for target delineation in resected high-grade gliomas before radiotherapy

AL Grosu, WA Weber, E Riedel, B Jeremic… - International Journal of …, 2005 - Elsevier
Purpose: Using magnetic resonance imaging (MRI), residual tumor cannot be differentiated
from nonspecific postoperative changes in operated patients with brain gliomas. The higher …

Correlation of l-methyl-11C-methionine (MET) uptake with l-type amino acid transporter 1 in human gliomas

S Okubo, HN Zhen, N Kawai, Y Nishiyama… - Journal of neuro …, 2010 - Springer
Abstract l-Type amino acid transporter 1 (LAT1) is a neutral amino acid transport system and
is a major route for the transport of large neutral amino acids, including methionine, through …

[PDF][PDF] Positron emission tomography for radiation treatment planning

AL Grosu, M Piert, WA Weber, B Jeremic… - Strahlentherapie und …, 2005 - academia.edu
Purpose: To evaluate the impact of positron emission tomography (PET) on target volume
delineation for radiation treatment planning. Material and Methods: The data of the literature …

Biological imaging in radiation therapy: role of positron emission tomography

U Nestle, W Weber, M Hentschel… - Physics in Medicine & …, 2008 - iopscience.iop.org
In radiation therapy (RT), staging, treatment planning, monitoring and evaluation of
response are traditionally based on computed tomography (CT) and magnetic resonance …

O-(2-[18F]fluorethyl)-L-tyrosine PET in the clinical evaluation of primary brain tumours

M Weckesser, KJ Langen, CH Rickert, S Kloska… - European journal of …, 2005 - Springer
Purpose The aim of this study was to evaluate the differential uptake of O-(2-[18 F] fluorethyl)-
L-tyrosine (FET) in suspected primary brain tumours. Methods Positron emission …

Imaging gliomas with positron emission tomography and single-photon emission computed tomography

F Bénard, J Romsa, R Hustinx - Seminars in nuclear medicine, 2003 - Elsevier
Over the last two decades the large volume of research involving various brain tracers has
shed invaluable light on the pathophysiology of cerebral neoplasms. Yet the question …