Dynamic whole-body PET imaging: principles, potentials and applications
Purpose In this article, we discuss dynamic whole-body (DWB) positron emission
tomography (PET) as an imaging tool with significant clinical potential, in relation to …
tomography (PET) as an imaging tool with significant clinical potential, in relation to …
First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients
Purpose To investigate the kinetics of 18 F-fluorodeoxyglucose (18 F-FDG) by positron
emission tomography (PET) in multiple organs and test the feasibility of total-body …
emission tomography (PET) in multiple organs and test the feasibility of total-body …
[HTML][HTML] Nuclear medicine preclinical research: the role of cell cultures
M Busk, S Sinning, AKO Alstrup, OL Munk… - Seminars in Nuclear …, 2023 - Elsevier
Cell lines are essential in biomedical research due to their adaptability and precise
simulation of physiological and pathophysiological conditions. Cell culture techniques have …
simulation of physiological and pathophysiological conditions. Cell culture techniques have …
Total-body quantitative parametric imaging of early kinetics of 18F-FDG
Parametric imaging has been shown to provide better quantitation physiologically than SUV
imaging in PET. With the increased sensitivity from a recently developed total-body PET …
imaging in PET. With the increased sensitivity from a recently developed total-body PET …
[HTML][HTML] Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis
K Kjærgaard, K Frisch, M Sørensen, OL Munk… - Journal of …, 2021 - Elsevier
Background & Aims Obeticholic acid (OCA) is an agonist of the nuclear bile acid receptor
farnesoid X receptor, which regulates hepatic bile acid metabolism. We tested whether OCA …
farnesoid X receptor, which regulates hepatic bile acid metabolism. We tested whether OCA …
[PDF][PDF] Brain metabolism of 13N‐ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography
S Keiding, M Sørensen, D Bender, OL Munk, P Ott… - …, 2006 - Wiley Online Library
Animal studies and results from 13N‐ammonia positron emission tomography (PET) in
patients with cirrhosis and minimal hepatic encephalopathy suggest that a disturbed brain …
patients with cirrhosis and minimal hepatic encephalopathy suggest that a disturbed brain …
Insulin stimulates liver glucose uptake in humans: an 18F-FDG PET Study
The liver is vital for the regulation of glucose metabolism, but inaccessibility of the organ for
direct assessments has limited the study of its metabolic role in vivo. Methods: The effect of …
direct assessments has limited the study of its metabolic role in vivo. Methods: The effect of …
[HTML][HTML] Intravenous and oral copper kinetics, biodistribution and dosimetry in healthy humans studied by [64Cu]copper PET/CT
K Kjærgaard, TD Sandahl, K Frisch, KH Vase… - EJNMMI …, 2020 - Springer
Purpose Copper is essential for enzymatic processes throughout the body.[64 Cu] copper
(64 Cu) positron emission tomography (PET) has been investigated as a diagnostic tool for …
(64 Cu) positron emission tomography (PET) has been investigated as a diagnostic tool for …
Insulin-mediated hepatic glucose uptake is impaired in type 2 diabetes: evidence for a relationship with glycemic control
Impaired hepatic glucose uptake (HGU) has been implicated in the development of
hyperglycemia in type 2 diabetes; the relative impact of plasma glucose and insulin levels …
hyperglycemia in type 2 diabetes; the relative impact of plasma glucose and insulin levels …
Dynamic PET of human liver inflammation: impact of kinetic modeling with optimization-derived dual-blood input function
The hallmark of nonalcoholic steatohepatitis is hepatocellular inflammation and injury in the
setting of hepatic steatosis. Recent work has indicated that dynamic 18 F-FDG PET with …
setting of hepatic steatosis. Recent work has indicated that dynamic 18 F-FDG PET with …